Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| F14H8.4 | eak-6 | F14H8.4.1 | F10G8.4b.1 | Uncharacterized protein. | Tyrosine-protein phosphatase non-receptor type eak-6; Putative phosphatase which, together with eak-4 and sdf-9, negatively regulates dauer larva formation downstream of insulin-like receptor daf-2 and in parallel of age-1, pdk-1 and akt-1. | 0.479 |
| T20B6.1 | Y39A3A.4 | T20B6.1.1 | Y39A3A.4.1 | Protein-tyrosine-phosphatase. | Tyrosine-protein phosphatase. | 0.521 |
| T20B6.1 | eak-6 | T20B6.1.1 | F10G8.4b.1 | Protein-tyrosine-phosphatase. | Tyrosine-protein phosphatase non-receptor type eak-6; Putative phosphatase which, together with eak-4 and sdf-9, negatively regulates dauer larva formation downstream of insulin-like receptor daf-2 and in parallel of age-1, pdk-1 and akt-1. | 0.523 |
| Y39A3A.4 | T20B6.1 | Y39A3A.4.1 | T20B6.1.1 | Tyrosine-protein phosphatase. | Protein-tyrosine-phosphatase. | 0.521 |
| Y39A3A.4 | eak-6 | Y39A3A.4.1 | F10G8.4b.1 | Tyrosine-protein phosphatase. | Tyrosine-protein phosphatase non-receptor type eak-6; Putative phosphatase which, together with eak-4 and sdf-9, negatively regulates dauer larva formation downstream of insulin-like receptor daf-2 and in parallel of age-1, pdk-1 and akt-1. | 0.482 |
| daf-2 | daf-9 | Y55D5A.5c.2 | T13C5.1a.1 | Insulin-like receptor subunit alpha; Insulin receptor-like tyrosine kinase which regulates metabolism, controls longevity and prevents developmental arrest at the dauer stage. Binding of INS family members may either stimulate, or antagonize, association of the receptor with downstream mediators such as pdk-1 and age-1. Required for germline progenitor proliferation during larval development. Required for the response to environmental stimuli such as food, pheromone, and temperature. Negatively regulates resistance to UV and oxidative stress. Role in immune function and pathogen resist [...] | Cytochrome P450 daf-9; Sterol hydroxylase that catalyzes the successive oxidization of the side chains of the 3-keto steroids 4-cholesten-3-one and lathosterone to form their carboxylic acid derivatives Delta(4)- dafachronic acid and Delta(7)-dafachronic acid respectively. Dafachronic acids bind directly to the nuclear hormone receptor (NHR) daf-12, suppressing dauer formation and inducing reproductive growth. In a non-cell autonomous manner, negatively regulates body wall muscle arm extensions to motor neurons probably by preventing daf-12 isoform b activation. May be involved in ther [...] | 0.828 |
| daf-2 | eak-6 | Y55D5A.5c.2 | F10G8.4b.1 | Insulin-like receptor subunit alpha; Insulin receptor-like tyrosine kinase which regulates metabolism, controls longevity and prevents developmental arrest at the dauer stage. Binding of INS family members may either stimulate, or antagonize, association of the receptor with downstream mediators such as pdk-1 and age-1. Required for germline progenitor proliferation during larval development. Required for the response to environmental stimuli such as food, pheromone, and temperature. Negatively regulates resistance to UV and oxidative stress. Role in immune function and pathogen resist [...] | Tyrosine-protein phosphatase non-receptor type eak-6; Putative phosphatase which, together with eak-4 and sdf-9, negatively regulates dauer larva formation downstream of insulin-like receptor daf-2 and in parallel of age-1, pdk-1 and akt-1. | 0.703 |
| daf-2 | eak-7 | Y55D5A.5c.2 | K08E7.1.2 | Insulin-like receptor subunit alpha; Insulin receptor-like tyrosine kinase which regulates metabolism, controls longevity and prevents developmental arrest at the dauer stage. Binding of INS family members may either stimulate, or antagonize, association of the receptor with downstream mediators such as pdk-1 and age-1. Required for germline progenitor proliferation during larval development. Required for the response to environmental stimuli such as food, pheromone, and temperature. Negatively regulates resistance to UV and oxidative stress. Role in immune function and pathogen resist [...] | TLDc domain-containing protein. | 0.461 |
| daf-9 | daf-2 | T13C5.1a.1 | Y55D5A.5c.2 | Cytochrome P450 daf-9; Sterol hydroxylase that catalyzes the successive oxidization of the side chains of the 3-keto steroids 4-cholesten-3-one and lathosterone to form their carboxylic acid derivatives Delta(4)- dafachronic acid and Delta(7)-dafachronic acid respectively. Dafachronic acids bind directly to the nuclear hormone receptor (NHR) daf-12, suppressing dauer formation and inducing reproductive growth. In a non-cell autonomous manner, negatively regulates body wall muscle arm extensions to motor neurons probably by preventing daf-12 isoform b activation. May be involved in ther [...] | Insulin-like receptor subunit alpha; Insulin receptor-like tyrosine kinase which regulates metabolism, controls longevity and prevents developmental arrest at the dauer stage. Binding of INS family members may either stimulate, or antagonize, association of the receptor with downstream mediators such as pdk-1 and age-1. Required for germline progenitor proliferation during larval development. Required for the response to environmental stimuli such as food, pheromone, and temperature. Negatively regulates resistance to UV and oxidative stress. Role in immune function and pathogen resist [...] | 0.828 |
| daf-9 | eak-3 | T13C5.1a.1 | Y92C3A.3.1 | Cytochrome P450 daf-9; Sterol hydroxylase that catalyzes the successive oxidization of the side chains of the 3-keto steroids 4-cholesten-3-one and lathosterone to form their carboxylic acid derivatives Delta(4)- dafachronic acid and Delta(7)-dafachronic acid respectively. Dafachronic acids bind directly to the nuclear hormone receptor (NHR) daf-12, suppressing dauer formation and inducing reproductive growth. In a non-cell autonomous manner, negatively regulates body wall muscle arm extensions to motor neurons probably by preventing daf-12 isoform b activation. May be involved in ther [...] | Enhancer of AKt-1 null. | 0.663 |
| daf-9 | eak-4 | T13C5.1a.1 | F53B2.3.1 | Cytochrome P450 daf-9; Sterol hydroxylase that catalyzes the successive oxidization of the side chains of the 3-keto steroids 4-cholesten-3-one and lathosterone to form their carboxylic acid derivatives Delta(4)- dafachronic acid and Delta(7)-dafachronic acid respectively. Dafachronic acids bind directly to the nuclear hormone receptor (NHR) daf-12, suppressing dauer formation and inducing reproductive growth. In a non-cell autonomous manner, negatively regulates body wall muscle arm extensions to motor neurons probably by preventing daf-12 isoform b activation. May be involved in ther [...] | Protein eak-4; Together with eak-6 and sdf-9, negatively regulates dauer larva formation downstream of insulin-like receptor daf-2 and in parallel with age-1, pdk-1 and akt-1. | 0.692 |
| daf-9 | eak-6 | T13C5.1a.1 | F10G8.4b.1 | Cytochrome P450 daf-9; Sterol hydroxylase that catalyzes the successive oxidization of the side chains of the 3-keto steroids 4-cholesten-3-one and lathosterone to form their carboxylic acid derivatives Delta(4)- dafachronic acid and Delta(7)-dafachronic acid respectively. Dafachronic acids bind directly to the nuclear hormone receptor (NHR) daf-12, suppressing dauer formation and inducing reproductive growth. In a non-cell autonomous manner, negatively regulates body wall muscle arm extensions to motor neurons probably by preventing daf-12 isoform b activation. May be involved in ther [...] | Tyrosine-protein phosphatase non-receptor type eak-6; Putative phosphatase which, together with eak-4 and sdf-9, negatively regulates dauer larva formation downstream of insulin-like receptor daf-2 and in parallel of age-1, pdk-1 and akt-1. | 0.581 |
| daf-9 | eak-7 | T13C5.1a.1 | K08E7.1.2 | Cytochrome P450 daf-9; Sterol hydroxylase that catalyzes the successive oxidization of the side chains of the 3-keto steroids 4-cholesten-3-one and lathosterone to form their carboxylic acid derivatives Delta(4)- dafachronic acid and Delta(7)-dafachronic acid respectively. Dafachronic acids bind directly to the nuclear hormone receptor (NHR) daf-12, suppressing dauer formation and inducing reproductive growth. In a non-cell autonomous manner, negatively regulates body wall muscle arm extensions to motor neurons probably by preventing daf-12 isoform b activation. May be involved in ther [...] | TLDc domain-containing protein. | 0.670 |
| daf-9 | hsd-1 | T13C5.1a.1 | Y6B3B.11.1 | Cytochrome P450 daf-9; Sterol hydroxylase that catalyzes the successive oxidization of the side chains of the 3-keto steroids 4-cholesten-3-one and lathosterone to form their carboxylic acid derivatives Delta(4)- dafachronic acid and Delta(7)-dafachronic acid respectively. Dafachronic acids bind directly to the nuclear hormone receptor (NHR) daf-12, suppressing dauer formation and inducing reproductive growth. In a non-cell autonomous manner, negatively regulates body wall muscle arm extensions to motor neurons probably by preventing daf-12 isoform b activation. May be involved in ther [...] | 3Beta_HSD domain-containing protein. | 0.905 |
| eak-3 | daf-9 | Y92C3A.3.1 | T13C5.1a.1 | Enhancer of AKt-1 null. | Cytochrome P450 daf-9; Sterol hydroxylase that catalyzes the successive oxidization of the side chains of the 3-keto steroids 4-cholesten-3-one and lathosterone to form their carboxylic acid derivatives Delta(4)- dafachronic acid and Delta(7)-dafachronic acid respectively. Dafachronic acids bind directly to the nuclear hormone receptor (NHR) daf-12, suppressing dauer formation and inducing reproductive growth. In a non-cell autonomous manner, negatively regulates body wall muscle arm extensions to motor neurons probably by preventing daf-12 isoform b activation. May be involved in ther [...] | 0.663 |
| eak-3 | eak-4 | Y92C3A.3.1 | F53B2.3.1 | Enhancer of AKt-1 null. | Protein eak-4; Together with eak-6 and sdf-9, negatively regulates dauer larva formation downstream of insulin-like receptor daf-2 and in parallel with age-1, pdk-1 and akt-1. | 0.902 |
| eak-3 | eak-6 | Y92C3A.3.1 | F10G8.4b.1 | Enhancer of AKt-1 null. | Tyrosine-protein phosphatase non-receptor type eak-6; Putative phosphatase which, together with eak-4 and sdf-9, negatively regulates dauer larva formation downstream of insulin-like receptor daf-2 and in parallel of age-1, pdk-1 and akt-1. | 0.913 |
| eak-3 | eak-7 | Y92C3A.3.1 | K08E7.1.2 | Enhancer of AKt-1 null. | TLDc domain-containing protein. | 0.810 |
| eak-3 | hsd-1 | Y92C3A.3.1 | Y6B3B.11.1 | Enhancer of AKt-1 null. | 3Beta_HSD domain-containing protein. | 0.704 |
| eak-4 | daf-9 | F53B2.3.1 | T13C5.1a.1 | Protein eak-4; Together with eak-6 and sdf-9, negatively regulates dauer larva formation downstream of insulin-like receptor daf-2 and in parallel with age-1, pdk-1 and akt-1. | Cytochrome P450 daf-9; Sterol hydroxylase that catalyzes the successive oxidization of the side chains of the 3-keto steroids 4-cholesten-3-one and lathosterone to form their carboxylic acid derivatives Delta(4)- dafachronic acid and Delta(7)-dafachronic acid respectively. Dafachronic acids bind directly to the nuclear hormone receptor (NHR) daf-12, suppressing dauer formation and inducing reproductive growth. In a non-cell autonomous manner, negatively regulates body wall muscle arm extensions to motor neurons probably by preventing daf-12 isoform b activation. May be involved in ther [...] | 0.692 |
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