Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| alg-1 | hbl-1 | F48F7.1b.1 | F13D11.2a.1 | Protein argonaute; Belongs to the argonaute family. | Hunchback-like protein; Required for the late stages of development. Plays a role in the developmental timing of postembryonic hypodermal seam cell fusion events and adult alae production. | 0.724 |
| alg-1 | lin-14 | F48F7.1b.1 | T25C12.1a.1 | Protein argonaute; Belongs to the argonaute family. | Protein lin-14; Heterochronic protein which controls the choice of stage specific cell fates. Involved in the temporal progression of vulval fate patterning, possibly by inhibiting lin-12. Acts as a transcription factor involved in the stage-specific repression of insulin/insulin- like growth factor gene ins-33. Isoform A may be involved in specifying L1 cell fates while isoform B1 and isoform B2 may specify L2 and later cell fates, creating a temporal switch. | 0.703 |
| alg-1 | lin-28 | F48F7.1b.1 | F02E9.2a.1 | Protein argonaute; Belongs to the argonaute family. | Protein lin-28; Heterochronic protein which controls the choice of stage specific cell fates. Regulates the timing of the second larval stage events (L2 events) in the hypodermis. May negatively regulate the larval to adult transition via the suppression of the microRNA (miRNA) let-7 during L3. Plays a role in the control of seam cell number and vulval development. Belongs to the lin-28 family. | 0.690 |
| alg-1 | lin-29 | F48F7.1b.1 | W03C9.4a.1 | Protein argonaute; Belongs to the argonaute family. | Transcription factor. | 0.494 |
| alg-1 | lin-41 | F48F7.1b.1 | C12C8.3a.1 | Protein argonaute; Belongs to the argonaute family. | Protein lin-41; Heterochronic protein which acts downstream of let-7 in temporal patterning. Plays a role in the developmental timing of postembryonic hypodermal seam cell division and fusion events and adult alae production. Represses lin-29 during late larval stages, which prevents terminal differentiation of hypodermal seam cells and promotes their division. Involved in post-transcriptional gene regulation, uses two independent pathways. Has direct and specific RNA-binding activity and, depending on the location (5'UTR or 3'UTR) of the target site, triggers either mRNA decay or repr [...] | 0.987 |
| alg-1 | nhl-2 | F48F7.1b.1 | F26F4.7.1 | Protein argonaute; Belongs to the argonaute family. | NHL (Ring finger b-box coiled coil) domain containing. | 0.879 |
| daf-12 | hbl-1 | F11A1.3a.1 | F13D11.2a.1 | Nuclear hormone receptor family member daf-12; Nuclear receptor which binds directly to response elements in target gene promoters. Activity is modulated by binding of steroid hormone ligands that include dafachronic acids. Regulates expression of genes involved in postembryonic development and the dauer diapause, in response to environmental cues. Inhibits the expression of let-7 family members when bound to corepressor din-1s which is an isoform of din-1. Has a role in the immune response to bacterial infection, via regulation of let-7 miRNAs. Controls expression of genes that promot [...] | Hunchback-like protein; Required for the late stages of development. Plays a role in the developmental timing of postembryonic hypodermal seam cell fusion events and adult alae production. | 0.821 |
| daf-12 | lin-14 | F11A1.3a.1 | T25C12.1a.1 | Nuclear hormone receptor family member daf-12; Nuclear receptor which binds directly to response elements in target gene promoters. Activity is modulated by binding of steroid hormone ligands that include dafachronic acids. Regulates expression of genes involved in postembryonic development and the dauer diapause, in response to environmental cues. Inhibits the expression of let-7 family members when bound to corepressor din-1s which is an isoform of din-1. Has a role in the immune response to bacterial infection, via regulation of let-7 miRNAs. Controls expression of genes that promot [...] | Protein lin-14; Heterochronic protein which controls the choice of stage specific cell fates. Involved in the temporal progression of vulval fate patterning, possibly by inhibiting lin-12. Acts as a transcription factor involved in the stage-specific repression of insulin/insulin- like growth factor gene ins-33. Isoform A may be involved in specifying L1 cell fates while isoform B1 and isoform B2 may specify L2 and later cell fates, creating a temporal switch. | 0.825 |
| daf-12 | lin-28 | F11A1.3a.1 | F02E9.2a.1 | Nuclear hormone receptor family member daf-12; Nuclear receptor which binds directly to response elements in target gene promoters. Activity is modulated by binding of steroid hormone ligands that include dafachronic acids. Regulates expression of genes involved in postembryonic development and the dauer diapause, in response to environmental cues. Inhibits the expression of let-7 family members when bound to corepressor din-1s which is an isoform of din-1. Has a role in the immune response to bacterial infection, via regulation of let-7 miRNAs. Controls expression of genes that promot [...] | Protein lin-28; Heterochronic protein which controls the choice of stage specific cell fates. Regulates the timing of the second larval stage events (L2 events) in the hypodermis. May negatively regulate the larval to adult transition via the suppression of the microRNA (miRNA) let-7 during L3. Plays a role in the control of seam cell number and vulval development. Belongs to the lin-28 family. | 0.810 |
| daf-12 | lin-29 | F11A1.3a.1 | W03C9.4a.1 | Nuclear hormone receptor family member daf-12; Nuclear receptor which binds directly to response elements in target gene promoters. Activity is modulated by binding of steroid hormone ligands that include dafachronic acids. Regulates expression of genes involved in postembryonic development and the dauer diapause, in response to environmental cues. Inhibits the expression of let-7 family members when bound to corepressor din-1s which is an isoform of din-1. Has a role in the immune response to bacterial infection, via regulation of let-7 miRNAs. Controls expression of genes that promot [...] | Transcription factor. | 0.759 |
| daf-12 | lin-41 | F11A1.3a.1 | C12C8.3a.1 | Nuclear hormone receptor family member daf-12; Nuclear receptor which binds directly to response elements in target gene promoters. Activity is modulated by binding of steroid hormone ligands that include dafachronic acids. Regulates expression of genes involved in postembryonic development and the dauer diapause, in response to environmental cues. Inhibits the expression of let-7 family members when bound to corepressor din-1s which is an isoform of din-1. Has a role in the immune response to bacterial infection, via regulation of let-7 miRNAs. Controls expression of genes that promot [...] | Protein lin-41; Heterochronic protein which acts downstream of let-7 in temporal patterning. Plays a role in the developmental timing of postembryonic hypodermal seam cell division and fusion events and adult alae production. Represses lin-29 during late larval stages, which prevents terminal differentiation of hypodermal seam cells and promotes their division. Involved in post-transcriptional gene regulation, uses two independent pathways. Has direct and specific RNA-binding activity and, depending on the location (5'UTR or 3'UTR) of the target site, triggers either mRNA decay or repr [...] | 0.816 |
| daf-12 | lin-42 | F11A1.3a.1 | F47F6.1d.1 | Nuclear hormone receptor family member daf-12; Nuclear receptor which binds directly to response elements in target gene promoters. Activity is modulated by binding of steroid hormone ligands that include dafachronic acids. Regulates expression of genes involved in postembryonic development and the dauer diapause, in response to environmental cues. Inhibits the expression of let-7 family members when bound to corepressor din-1s which is an isoform of din-1. Has a role in the immune response to bacterial infection, via regulation of let-7 miRNAs. Controls expression of genes that promot [...] | Period protein homolog lin-42; Transcriptional repressor which interacts with the promoter region of target genes. Has a specific role in developmental timing where it regulates temporal expression of a number of miRNAs and mRNAs. Controls temporal cell fate transition during embryonic and early larval development by restricting the expression of specific miRNAs, including let-7, miR-48, lin-4, miR-35 and miR-58. Restricts the accumulation of lin-29 in the hypodermis to the larval L4 stage, thus controlling terminal differentiation of seam cells. Has a role in the miRNA-mediated specif [...] | 0.855 |
| daf-12 | lin-46 | F11A1.3a.1 | R186.4.1 | Nuclear hormone receptor family member daf-12; Nuclear receptor which binds directly to response elements in target gene promoters. Activity is modulated by binding of steroid hormone ligands that include dafachronic acids. Regulates expression of genes involved in postembryonic development and the dauer diapause, in response to environmental cues. Inhibits the expression of let-7 family members when bound to corepressor din-1s which is an isoform of din-1. Has a role in the immune response to bacterial infection, via regulation of let-7 miRNAs. Controls expression of genes that promot [...] | Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. | 0.461 |
| hbl-1 | alg-1 | F13D11.2a.1 | F48F7.1b.1 | Hunchback-like protein; Required for the late stages of development. Plays a role in the developmental timing of postembryonic hypodermal seam cell fusion events and adult alae production. | Protein argonaute; Belongs to the argonaute family. | 0.724 |
| hbl-1 | daf-12 | F13D11.2a.1 | F11A1.3a.1 | Hunchback-like protein; Required for the late stages of development. Plays a role in the developmental timing of postembryonic hypodermal seam cell fusion events and adult alae production. | Nuclear hormone receptor family member daf-12; Nuclear receptor which binds directly to response elements in target gene promoters. Activity is modulated by binding of steroid hormone ligands that include dafachronic acids. Regulates expression of genes involved in postembryonic development and the dauer diapause, in response to environmental cues. Inhibits the expression of let-7 family members when bound to corepressor din-1s which is an isoform of din-1. Has a role in the immune response to bacterial infection, via regulation of let-7 miRNAs. Controls expression of genes that promot [...] | 0.821 |
| hbl-1 | lin-14 | F13D11.2a.1 | T25C12.1a.1 | Hunchback-like protein; Required for the late stages of development. Plays a role in the developmental timing of postembryonic hypodermal seam cell fusion events and adult alae production. | Protein lin-14; Heterochronic protein which controls the choice of stage specific cell fates. Involved in the temporal progression of vulval fate patterning, possibly by inhibiting lin-12. Acts as a transcription factor involved in the stage-specific repression of insulin/insulin- like growth factor gene ins-33. Isoform A may be involved in specifying L1 cell fates while isoform B1 and isoform B2 may specify L2 and later cell fates, creating a temporal switch. | 0.912 |
| hbl-1 | lin-28 | F13D11.2a.1 | F02E9.2a.1 | Hunchback-like protein; Required for the late stages of development. Plays a role in the developmental timing of postembryonic hypodermal seam cell fusion events and adult alae production. | Protein lin-28; Heterochronic protein which controls the choice of stage specific cell fates. Regulates the timing of the second larval stage events (L2 events) in the hypodermis. May negatively regulate the larval to adult transition via the suppression of the microRNA (miRNA) let-7 during L3. Plays a role in the control of seam cell number and vulval development. Belongs to the lin-28 family. | 0.897 |
| hbl-1 | lin-29 | F13D11.2a.1 | W03C9.4a.1 | Hunchback-like protein; Required for the late stages of development. Plays a role in the developmental timing of postembryonic hypodermal seam cell fusion events and adult alae production. | Transcription factor. | 0.875 |
| hbl-1 | lin-41 | F13D11.2a.1 | C12C8.3a.1 | Hunchback-like protein; Required for the late stages of development. Plays a role in the developmental timing of postembryonic hypodermal seam cell fusion events and adult alae production. | Protein lin-41; Heterochronic protein which acts downstream of let-7 in temporal patterning. Plays a role in the developmental timing of postembryonic hypodermal seam cell division and fusion events and adult alae production. Represses lin-29 during late larval stages, which prevents terminal differentiation of hypodermal seam cells and promotes their division. Involved in post-transcriptional gene regulation, uses two independent pathways. Has direct and specific RNA-binding activity and, depending on the location (5'UTR or 3'UTR) of the target site, triggers either mRNA decay or repr [...] | 0.920 |
| hbl-1 | lin-42 | F13D11.2a.1 | F47F6.1d.1 | Hunchback-like protein; Required for the late stages of development. Plays a role in the developmental timing of postembryonic hypodermal seam cell fusion events and adult alae production. | Period protein homolog lin-42; Transcriptional repressor which interacts with the promoter region of target genes. Has a specific role in developmental timing where it regulates temporal expression of a number of miRNAs and mRNAs. Controls temporal cell fate transition during embryonic and early larval development by restricting the expression of specific miRNAs, including let-7, miR-48, lin-4, miR-35 and miR-58. Restricts the accumulation of lin-29 in the hypodermis to the larval L4 stage, thus controlling terminal differentiation of seam cells. Has a role in the miRNA-mediated specif [...] | 0.746 |
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