STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dmd-6DM domain-containing protein. (470 aa)    
Predicted Functional Partners:
dmd-4
DM domain-containing protein.
      
 0.805
dmd-8
DM (Doublesex/MAB-3) Domain family.
    
 
 0.729
dmd-10
DM domain-containing protein.
      
 0.693
dmd-5
DM domain-containing protein.
    
 
 0.569
pat-9
Paralysed Arrest at Two-fold.
   
  
 0.540
dmd-11
DM domain-containing protein.
      
 0.537
mbr-1
Mblk-1-related factor 1; May act as transcription activator (By similarity). Plays a role in neurogenesis by regulating neurite pruning between left and right AIM neurons and left and right RIF neurons during larval development. Regulates olfactory plasticity.
    
 
 0.510
pes-1
Fork-head domain-containing protein.
      
 0.475
dmd-3
Doublesex- and mab-3-related transcription factor dmd-3; Transcriptional activator which promotes male-specific development. Acts partially redundantly with the transcription factor mab-3 to coordinate tail tip cell fusion and retraction and thereby regulate male tail tip morphogenesis. This is most likely through the regulation of downstream effectors such as eff-1. May also negatively regulate the expression of other proteins implicated in male tail morphogenesis including nhr-25, vav-1 and arl-1 in tail tip cells. In males, plays a role in the development of ray A-neurons by negativ [...]
    
 
 0.459
zip-7
BZIP domain-containing protein.
    
   0.450
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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