STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dsl-7Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (313 aa)    
Predicted Functional Partners:
C02B10.3
EGF-like domain-containing protein C02B10.3.
   
  
 0.861
apx-1
Anterior pharynx in excess protein 1; Involved in the specification of the blastomere cell ABP fate. Contributes to the establishment of the dorsal-ventral axis in the early embryo.
      
 0.741
arg-1
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
      
 0.699
dos-3
Delta and OSM-11-like.
      
 0.697
T22C1.3
PhosphatidylInositol Glycan anchor biosynthesis class T.
      
 0.533
C27A12.9
PhosphatidylInositol Glycan anchor biosynthesis class O.
      
 0.530
rig-6
Contactin rig-6; Probable cell adhesion protein involved in patterning of the nervous system, playing a role in ALM and PLM touch receptor axon growth and VNC axon navigation. By associating with the transmembrane protein sax-7, mediates axonal interactions to establish synaptic connections between the AVG interneuron and the two PHC sensory neurons. Also required for non-neuronal cell migration in the excretory canal, regulating excretory canal elongation and excretory cell morphogenesis. Plays a role in regulating male mating behavior.
   
  
 0.506
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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