STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pud-2.2Protein Up-regulated in Daf-2(Gf). (154 aa)    
Predicted Functional Partners:
pud-1.2
Protein Up-regulated in Daf-2(Gf).
   
 
0.961
pud-1.1
PUD1_2 domain-containing protein.
    
 
0.912
pud-2.1
Protein Up-regulated in Daf-2(Gf).
   
  
0.911
C32H11.9
CUB_2 domain-containing protein.
      
 0.850
dod-21
CUB_2 domain-containing protein.
      
 0.696
C32H11.4
CUB_2 domain-containing protein.
   
  
 0.679
ndk-1
Nucleoside diphosphate kinase; Belongs to the NDK family.
      
 0.660
iff-1
Eukaryotic translation initiation factor 5A-1; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis (By similarity). Required for mitotic germ cell proliferation, gametogenesis after entry into meiosis, and localization of the P granule component pgl-1 on P granules; Belongs to the eIF-5A family.
      
 0.615
pud-3
PUD1_2 domain-containing protein.
   
   
0.538
C49H3.4
Sm domain-containing protein.
      
 0.529
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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