STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nekl-3Serine/threonine-protein kinase nekl-3; Probable serine/threonine-protein kinase required for the completion of molting; Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily. (302 aa)    
Predicted Functional Partners:
mlt-3
ANK_REP_REGION domain-containing protein.
   
 
 0.929
mlt-2
ANK_REP_REGION domain-containing protein.
   
 
 0.905
mlt-4
ANK_REP_REGION domain-containing protein.
   
 
 0.874
C27F2.9
JmjC domain-containing protein.
      
 0.806
nhr-85
Nuclear hormone receptor family member nhr-85; Orphan nuclear receptor.
   
  
 0.697
adm-2
ADAM (Disintegrin plus metalloprotease) family.
      
 0.693
ncap-1
DUF1681 domain-containing protein.
      
 0.691
btb-14
BTB/POZ domain-containing protein Y57A10B.3.
   
  
 0.674
T02G5.3
EF-hand domain-containing protein.
      
 0.669
uso-1
USO1 (Yeast transport protein) homolog.
      
 0.666
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.