node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F59B2.3 | T03F6.3 | F59B2.3.3 | T03F6.3.1 | N-acetylglucosamine-6-phosphate deacetylase; Belongs to the metallo-dependent hydrolases superfamily. NagA family. | Probable glucosamine-6-phosphate isomerase. | 0.999 |
F59B2.3 | gfat-2 | F59B2.3.3 | F22B3.4.2 | N-acetylglucosamine-6-phosphate deacetylase; Belongs to the metallo-dependent hydrolases superfamily. NagA family. | Glutamine-Fructose 6-phosphate AminoTransferase homolog. | 0.997 |
T01C3.3 | cbd-1 | T01C3.3.1 | H02I12.1.1 | RING-type domain-containing protein. | Chitin-binding domain protein cbd-1; In unfertilized oocytes, maintains egg-1 and egg-2 at the plasma membrane together with chitin synthase chs-1 and kinase mbk-2. Essential for the formation of a continuous and cohesive chitin layer following fertilization. | 0.903 |
T01C3.3 | cpg-3 | T01C3.3.1 | R06C7.4.3 | RING-type domain-containing protein. | Chondroitin proteoglycan 3. | 0.999 |
T01C3.3 | egg-1 | T01C3.3.1 | B0244.8.1 | RING-type domain-containing protein. | LDL receptor repeat-containing protein egg-1; Probable receptor which is required for the oocyte-to-zygote transition although its exact function is controversial. Redundantly with egg-2, seems to be required for fertilization probably by promoting the interaction or fusion between sperm and oocyte. Conversely, shown to be dispensable for fertilization but required together with egg-2 for the formation of a continuous and cohesive eggshell chitin layer by maintaining a homogenous distribution of chitin synthase chs-1 at the unfertilized oocyte cell membrane. Appears to recruit or maint [...] | 0.999 |
T01C3.3 | gfat-2 | T01C3.3.1 | F22B3.4.2 | RING-type domain-containing protein. | Glutamine-Fructose 6-phosphate AminoTransferase homolog. | 0.999 |
T01C3.3 | gln-5 | T01C3.3.1 | F26D10.10.1 | RING-type domain-containing protein. | Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family. | 0.999 |
T01C3.3 | mesp-1 | T01C3.3.1 | C28C12.2.1 | RING-type domain-containing protein. | MEiotic SPindle. | 0.999 |
T01C3.3 | oma-2 | T01C3.3.1 | ZC513.6.1 | RING-type domain-containing protein. | CCCH-type zinc finger protein oma-2; Zinc-finger RNA-binding protein that binds to 5'-UA[AU]-3' motifs in the 3'-UTR of maternal mRNAs to suppress translation in oocytes and embryos. Acts redundantly with oma-1 to control the temporal expression and distribution of maternal proteins and thereby promote meiotic progression, oocyte maturation, fertilization and embryonic development. Also, together with oma-1, is involved in P-granule distribution during embryonic development. | 0.999 |
T01C3.3 | puf-3 | T01C3.3.1 | Y45F10A.2.1 | RING-type domain-containing protein. | PUM-HD domain-containing protein. | 0.999 |
T03F6.3 | F59B2.3 | T03F6.3.1 | F59B2.3.3 | Probable glucosamine-6-phosphate isomerase. | N-acetylglucosamine-6-phosphate deacetylase; Belongs to the metallo-dependent hydrolases superfamily. NagA family. | 0.999 |
T03F6.3 | gfat-2 | T03F6.3.1 | F22B3.4.2 | Probable glucosamine-6-phosphate isomerase. | Glutamine-Fructose 6-phosphate AminoTransferase homolog. | 0.996 |
cbd-1 | T01C3.3 | H02I12.1.1 | T01C3.3.1 | Chitin-binding domain protein cbd-1; In unfertilized oocytes, maintains egg-1 and egg-2 at the plasma membrane together with chitin synthase chs-1 and kinase mbk-2. Essential for the formation of a continuous and cohesive chitin layer following fertilization. | RING-type domain-containing protein. | 0.903 |
cbd-1 | cpg-3 | H02I12.1.1 | R06C7.4.3 | Chitin-binding domain protein cbd-1; In unfertilized oocytes, maintains egg-1 and egg-2 at the plasma membrane together with chitin synthase chs-1 and kinase mbk-2. Essential for the formation of a continuous and cohesive chitin layer following fertilization. | Chondroitin proteoglycan 3. | 0.999 |
cbd-1 | egg-1 | H02I12.1.1 | B0244.8.1 | Chitin-binding domain protein cbd-1; In unfertilized oocytes, maintains egg-1 and egg-2 at the plasma membrane together with chitin synthase chs-1 and kinase mbk-2. Essential for the formation of a continuous and cohesive chitin layer following fertilization. | LDL receptor repeat-containing protein egg-1; Probable receptor which is required for the oocyte-to-zygote transition although its exact function is controversial. Redundantly with egg-2, seems to be required for fertilization probably by promoting the interaction or fusion between sperm and oocyte. Conversely, shown to be dispensable for fertilization but required together with egg-2 for the formation of a continuous and cohesive eggshell chitin layer by maintaining a homogenous distribution of chitin synthase chs-1 at the unfertilized oocyte cell membrane. Appears to recruit or maint [...] | 0.999 |
cbd-1 | gfat-2 | H02I12.1.1 | F22B3.4.2 | Chitin-binding domain protein cbd-1; In unfertilized oocytes, maintains egg-1 and egg-2 at the plasma membrane together with chitin synthase chs-1 and kinase mbk-2. Essential for the formation of a continuous and cohesive chitin layer following fertilization. | Glutamine-Fructose 6-phosphate AminoTransferase homolog. | 0.999 |
cbd-1 | gln-5 | H02I12.1.1 | F26D10.10.1 | Chitin-binding domain protein cbd-1; In unfertilized oocytes, maintains egg-1 and egg-2 at the plasma membrane together with chitin synthase chs-1 and kinase mbk-2. Essential for the formation of a continuous and cohesive chitin layer following fertilization. | Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family. | 0.999 |
cbd-1 | mesp-1 | H02I12.1.1 | C28C12.2.1 | Chitin-binding domain protein cbd-1; In unfertilized oocytes, maintains egg-1 and egg-2 at the plasma membrane together with chitin synthase chs-1 and kinase mbk-2. Essential for the formation of a continuous and cohesive chitin layer following fertilization. | MEiotic SPindle. | 0.999 |
cbd-1 | oma-2 | H02I12.1.1 | ZC513.6.1 | Chitin-binding domain protein cbd-1; In unfertilized oocytes, maintains egg-1 and egg-2 at the plasma membrane together with chitin synthase chs-1 and kinase mbk-2. Essential for the formation of a continuous and cohesive chitin layer following fertilization. | CCCH-type zinc finger protein oma-2; Zinc-finger RNA-binding protein that binds to 5'-UA[AU]-3' motifs in the 3'-UTR of maternal mRNAs to suppress translation in oocytes and embryos. Acts redundantly with oma-1 to control the temporal expression and distribution of maternal proteins and thereby promote meiotic progression, oocyte maturation, fertilization and embryonic development. Also, together with oma-1, is involved in P-granule distribution during embryonic development. | 0.999 |
cbd-1 | puf-3 | H02I12.1.1 | Y45F10A.2.1 | Chitin-binding domain protein cbd-1; In unfertilized oocytes, maintains egg-1 and egg-2 at the plasma membrane together with chitin synthase chs-1 and kinase mbk-2. Essential for the formation of a continuous and cohesive chitin layer following fertilization. | PUM-HD domain-containing protein. | 0.999 |