node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
air-1 | bmk-1 | K07C11.2.2 | F23B12.8b.1 | Protein kinase domain-containing protein. | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | 0.855 |
air-1 | ebp-1 | K07C11.2.2 | Y59A8B.7.1 | Protein kinase domain-containing protein. | Microtubule End Binding Protein. | 0.581 |
air-1 | ebp-2 | K07C11.2.2 | VW02B12L.3.2 | Protein kinase domain-containing protein. | Microtubule End Binding Protein. | 0.703 |
air-1 | ebp-3 | K07C11.2.2 | Y59A8B.9.1 | Protein kinase domain-containing protein. | EB1 C-terminal domain-containing protein. | 0.581 |
air-1 | him-10 | K07C11.2.2 | R12B2.4.1 | Protein kinase domain-containing protein. | Kinetochore protein Nuf2 homolog; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation in mitosis and meiosis and spindle checkpoint activity. The ndc-80 complex synergistically enhances the affinity of the ska-1 complex for microtubules and may allow the ndc-80 complex to track depolymerizing microtubules. Belongs to the NUF2 family. | 0.749 |
air-1 | ndc-80 | K07C11.2.2 | W01B6.9.1 | Protein kinase domain-containing protein. | Kinetochore protein ndc-80; Acts as a component of the essential kinetochore-associated ndc-80 complex, which is required for chromosome segregation in mitosis and meiosis and spindle checkpoint activity. Plays a role in kinetochore assembly and recruits the checkpoint protein mdf-2 and the spindly-like protein spdl-1 to unattached kinetochores. Mediates the formation of end-on kinetochore-microtubule attachments through recruitment of spdl-1. The ndc-80 complex synergistically enhances the affinity of the ska-1 complex for microtubules and may allow the ndc-80 complex to track depolym [...] | 0.884 |
air-1 | spd-5 | K07C11.2.2 | F56A3.4.1 | Protein kinase domain-containing protein. | Spindle-defective protein 5; Plays a central role in centrosome maturation and mitotic spindle assembly during the first division of the zygote. Required for the centrosomal localization of air-1 and zyg-9. Probably not required in late embryogenesis and during larval development. | 0.914 |
air-1 | tac-1 | K07C11.2.2 | Y54E2A.3.1 | Protein kinase domain-containing protein. | Transforming acid coiled-coil-containing protein 1; Involved in microtubule formation, polymerization and assembly, regulating microtubule nucleation and length. Plays a role in pronuclear migration and mitotic and meiotic spindle elongation during early embryogenesis. In complex with zyg-9, functions during the early stages of embryonic development to regulate microtubule assembly throughout the cell cycle. Specifically, the complex is required for the formation and growth of astral microtubules and spindle microtubules during mitotic spindle assembly. At anaphase, the complex is requ [...] | 0.943 |
air-1 | tpxl-1 | K07C11.2.2 | Y39G10AR.12a.1 | Protein kinase domain-containing protein. | TPX2 (Targeting Protein for Xenopus Klp2)-Like. | 0.967 |
air-1 | zyg-9 | K07C11.2.2 | F22B5.7.1 | Protein kinase domain-containing protein. | Zygote defective protein 9; Plays a major role in organizing microtubules and spindle poles during mitosis and meiosis in one-cell stage embryos. Required for default nucleus positioning in oocytes. | 0.899 |
bmk-1 | air-1 | F23B12.8b.1 | K07C11.2.2 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Protein kinase domain-containing protein. | 0.855 |
bmk-1 | ebp-1 | F23B12.8b.1 | Y59A8B.7.1 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Microtubule End Binding Protein. | 0.468 |
bmk-1 | ebp-2 | F23B12.8b.1 | VW02B12L.3.2 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Microtubule End Binding Protein. | 0.480 |
bmk-1 | ebp-3 | F23B12.8b.1 | Y59A8B.9.1 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | EB1 C-terminal domain-containing protein. | 0.468 |
bmk-1 | him-10 | F23B12.8b.1 | R12B2.4.1 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Kinetochore protein Nuf2 homolog; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation in mitosis and meiosis and spindle checkpoint activity. The ndc-80 complex synergistically enhances the affinity of the ska-1 complex for microtubules and may allow the ndc-80 complex to track depolymerizing microtubules. Belongs to the NUF2 family. | 0.960 |
bmk-1 | ndc-80 | F23B12.8b.1 | W01B6.9.1 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Kinetochore protein ndc-80; Acts as a component of the essential kinetochore-associated ndc-80 complex, which is required for chromosome segregation in mitosis and meiosis and spindle checkpoint activity. Plays a role in kinetochore assembly and recruits the checkpoint protein mdf-2 and the spindly-like protein spdl-1 to unattached kinetochores. Mediates the formation of end-on kinetochore-microtubule attachments through recruitment of spdl-1. The ndc-80 complex synergistically enhances the affinity of the ska-1 complex for microtubules and may allow the ndc-80 complex to track depolym [...] | 0.944 |
bmk-1 | tac-1 | F23B12.8b.1 | Y54E2A.3.1 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Transforming acid coiled-coil-containing protein 1; Involved in microtubule formation, polymerization and assembly, regulating microtubule nucleation and length. Plays a role in pronuclear migration and mitotic and meiotic spindle elongation during early embryogenesis. In complex with zyg-9, functions during the early stages of embryonic development to regulate microtubule assembly throughout the cell cycle. Specifically, the complex is required for the formation and growth of astral microtubules and spindle microtubules during mitotic spindle assembly. At anaphase, the complex is requ [...] | 0.690 |
bmk-1 | zyg-9 | F23B12.8b.1 | F22B5.7.1 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Zygote defective protein 9; Plays a major role in organizing microtubules and spindle poles during mitosis and meiosis in one-cell stage embryos. Required for default nucleus positioning in oocytes. | 0.871 |
ebp-1 | air-1 | Y59A8B.7.1 | K07C11.2.2 | Microtubule End Binding Protein. | Protein kinase domain-containing protein. | 0.581 |
ebp-1 | bmk-1 | Y59A8B.7.1 | F23B12.8b.1 | Microtubule End Binding Protein. | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | 0.468 |