STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lhfp-4Lipoma Hmgic (HMGIC) Fusion Partner-like homolog. (229 aa)    
Predicted Functional Partners:
cdh-5
CaDHerin family.
   
 
 0.935
sol-2
Suppressor Of Lurcher movement defect.
      
 0.853
molo-1
Uncharacterized protein.
      
 0.852
lev-9
Protein lev-9; Scaffolding protein that is necessary to cluster acetylcholine receptors at neuromuscular junctions.
   
  
 0.813
lev-10
LEV-10A protein.
      
 0.758
fkb-6
Peptidylprolyl isomerase.
   
  
 0.686
unc-79
Uncoordinated protein 79.
   
  
 0.685
gcs-1
Glutamate--cysteine ligase; Plays a role in resistance to arsenite. May play a role in the oxidative stress response induced by reactive oxygen species produced during infection by pathogenic bacteria. Together with trxr-1, required for the reduction of disulfide groups in the cuticle during molting.
      
 0.555
tub-1
Tubby protein homolog 1; Has a role in fat regulation independent of daf-16. Implicated in ciliar sensory function which is required for normal sensory behavior such as chemotaxis. Functions in life span control via the insulin/IGF-1 pathway. Thought to be involved in neuronal trafficking.
   
  
 0.535
cogc-6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
      
 0.478
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (20%) [HD]