STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
suf-1Suf domain-containing protein. (735 aa)    
Predicted Functional Partners:
cpf-1
WD_REPEATS_REGION domain-containing protein.
   
 0.998
symk-1
SYMpleKin cleavage and polyadenylation factor.
   
 0.997
fipp-1
Fip1 domain-containing protein.
   
 0.997
pfs-2
pre-mRNA 3' end processing protein pfs-2; Essential for both cleavage and polyadenylation of pre-mRNA 3' ends (By similarity). Involved in neuron development, probably by regulating pre-mRNA 3'-end processing.
   
 0.994
cpsf-4
Cleavage and Polyadenylation Specificity Factor.
    
 0.989
pcf-11
Polyadenylation and cleavage factor homolog 11.
   
 0.988
cpf-2
RRM domain-containing protein.
   
 0.986
enol-1
Enolase; Belongs to the enolase family.
  
 
 0.983
cpsf-1
Probable cleavage and polyadenylation specificity factor subunit 1; CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity).
   
 0.981
pgk-1
Probable phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
  
 
 0.977
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.