STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
atz-1Uncharacterized protein. (268 aa)    
Predicted Functional Partners:
ZK1053.4
Uncharacterized protein.
   
    0.846
myo-1
Myosin-1; Muscle contraction.
      
 0.811
rec-8
Meiotic recombination protein rec-8; Plays a role in meiotic chromosome cohesion and segregation. Necessary for sister chromatid co- orientation and sister chromatid cohension until meiosis II. May also be required for repair of programmed meiotic double stranded breaks. During spermatogenesis, likely involved in spermatocyte centriole cohesion, thus preventing their separation during the second meiotic division. Belongs to the rad21 family. Highly divergent.
      
 0.773
C35E7.5
Uncharacterized protein.
   
    0.615
Y82E9BR.17
Uncharacterized protein.
   
    0.615
meg-4
Uncharacterized protein.
   
   0.609
inx-2
Innexin-2; Structural component of the gap junctions. Belongs to the pannexin family.
   
    0.604
C08F1.10
Uncharacterized protein.
   
    0.602
C08F1.6
Uncharacterized protein.
   
    0.592
clec-266
C-type lectin domain-containing protein.
   
    0.585
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.