STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dhs-17DeHydrogenases, Short chain. (286 aa)    
Predicted Functional Partners:
B0034.5
G_PROTEIN_RECEP_F1_2 domain-containing protein.
      
 0.882
F52E1.5
Uncharacterized protein.
    
 
 0.860
C06A1.3
Putative serine/threonine-protein phosphatase C06A1.3.
      
 0.852
F14H8.2
Uncharacterized protein.
      
 0.850
pks-1
PolyKetide Synthase.
  
 0.839
T22E5.6
Uncharacterized protein.
      
 0.810
twk-39
TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
      
 0.808
lgc-36
Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.699
eak-4
Protein eak-4; Together with eak-6 and sdf-9, negatively regulates dauer larva formation downstream of insulin-like receptor daf-2 and in parallel with age-1, pdk-1 and akt-1.
      
 0.697
sdf-9
Protein sdf-9; Together with eak-4 and phosphatase eak-6, negatively regulates dauer larva formation downstream of insulin-like receptor daf-2 and in parallel of age-1, pdk-1 and akt-1.
      
 0.667
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.