STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nprl-3GATOR complex protein NPRL3; As a component of the GATOR complex may function in the amino acid-sensing branch of the TORC1 signaling pathway. (511 aa)    
Predicted Functional Partners:
nprl-2
Nitrogen Permease Regulator Like homolog.
   
 0.999
T08A11.1
DEP domain-containing protein.
   
 0.997
raga-1
RAs-related GTP-binding protein A.
   
 0.996
npp-18
Nucleoporin SEH1; Probable component of the nuclear pore complex (NPC) which is involved in the trafficking of macromolecules between the cytoplasm and nucleus.
   
 0.995
Y32H12A.8
WD_REPEATS_REGION domain-containing protein.
    
 
 0.994
npp-20
Protein SEC13 homolog; Functions as a component of the nuclear pore complex (NPC) and the COPII coat (By similarity). Required for the nuclear import of hcp-4 during mitotic prophase, this step is essential for centrosome assembly and resolution. Belongs to the WD repeat SEC13 family.
   
 0.987
ragc-1
RAs-related GTP binding protein C homolog.
   
 
 0.950
lmp-1
LAMP family protein lmp-1; Belongs to the LAMP family.
   
 
 0.862
lmp-2
LAMP (Lysosome-associated membrane protein) homolog.
    
 
 0.861
F39C12.1
Zinc_ribbon_16 domain-containing protein.
   
 
 0.849
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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