node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
daf-16 | hsf-1 | R13H8.1h.1 | Y53C10A.12.1 | Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] | HSF_DOMAIN domain-containing protein. | 0.927 |
daf-16 | hsp-12.6 | R13H8.1h.1 | F38E11.2.1 | Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] | SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. | 0.809 |
daf-16 | hsp-16.1 | R13H8.1h.1 | T27E4.8.1 | Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] | Heat shock protein Hsp-16.1/Hsp-16.11. | 0.761 |
daf-16 | hsp-16.11 | R13H8.1h.1 | T27E4.2.1 | Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] | Heat shock protein Hsp-16.1/Hsp-16.11. | 0.807 |
daf-16 | hsp-16.2 | R13H8.1h.1 | Y46H3A.3a.1 | Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] | Heat shock protein Hsp-16.2; Belongs to the small heat shock protein (HSP20) family. | 0.913 |
daf-16 | hsp-16.48 | R13H8.1h.1 | T27E4.3.1 | Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] | Heat shock protein Hsp-16.48/Hsp-16.49; Belongs to the small heat shock protein (HSP20) family. | 0.543 |
daf-16 | hsp-16.49 | R13H8.1h.1 | T27E4.9.1 | Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] | Heat shock protein Hsp-16.48/Hsp-16.49. | 0.537 |
daf-16 | sip-1 | R13H8.1h.1 | F43D9.4.1 | Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] | Stress-induced protein 1; Belongs to the small heat shock protein (HSP20) family. | 0.588 |
daf-16 | sod-3 | R13H8.1h.1 | C08A9.1.1 | Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] | Superoxide dismutase [Mn] 2, mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. | 0.935 |
hsf-1 | daf-16 | Y53C10A.12.1 | R13H8.1h.1 | HSF_DOMAIN domain-containing protein. | Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] | 0.927 |
hsf-1 | hsp-12.6 | Y53C10A.12.1 | F38E11.2.1 | HSF_DOMAIN domain-containing protein. | SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. | 0.858 |
hsf-1 | hsp-16.1 | Y53C10A.12.1 | T27E4.8.1 | HSF_DOMAIN domain-containing protein. | Heat shock protein Hsp-16.1/Hsp-16.11. | 0.836 |
hsf-1 | hsp-16.11 | Y53C10A.12.1 | T27E4.2.1 | HSF_DOMAIN domain-containing protein. | Heat shock protein Hsp-16.1/Hsp-16.11. | 0.897 |
hsf-1 | hsp-16.2 | Y53C10A.12.1 | Y46H3A.3a.1 | HSF_DOMAIN domain-containing protein. | Heat shock protein Hsp-16.2; Belongs to the small heat shock protein (HSP20) family. | 0.935 |
hsf-1 | hsp-16.41 | Y53C10A.12.1 | Y46H3A.2.1 | HSF_DOMAIN domain-containing protein. | Heat shock protein Hsp-16.41; Belongs to the small heat shock protein (HSP20) family. | 0.635 |
hsf-1 | hsp-16.48 | Y53C10A.12.1 | T27E4.3.1 | HSF_DOMAIN domain-containing protein. | Heat shock protein Hsp-16.48/Hsp-16.49; Belongs to the small heat shock protein (HSP20) family. | 0.819 |
hsf-1 | hsp-16.49 | Y53C10A.12.1 | T27E4.9.1 | HSF_DOMAIN domain-containing protein. | Heat shock protein Hsp-16.48/Hsp-16.49. | 0.705 |
hsf-1 | sip-1 | Y53C10A.12.1 | F43D9.4.1 | HSF_DOMAIN domain-containing protein. | Stress-induced protein 1; Belongs to the small heat shock protein (HSP20) family. | 0.833 |
hsf-1 | sod-3 | Y53C10A.12.1 | C08A9.1.1 | HSF_DOMAIN domain-containing protein. | Superoxide dismutase [Mn] 2, mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. | 0.806 |
hsp-12.6 | daf-16 | F38E11.2.1 | R13H8.1h.1 | SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. | Forkhead box protein O; Forkhead-type transcription factor. Binds to the promoters of genes that contain the daf-16 binding element (DBE), TTGTTTAC, in their regulatory region. Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway which affects lipogenesis, lifespan, starvation survival, heat shock and oxidative stress responses, and dauer formation. Longevity signaling predominantly arises from expression in the intestine. Daf-16 transcriptional activity is negatively regulated by cytoplasmic sequestration by association with ftt-2. Inhibition is required for the carbon [...] | 0.809 |