STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
srx-1057TM_GPCR_Srx domain-containing protein. (305 aa)    
Predicted Functional Partners:
F19B10.10
Uncharacterized protein.
      
 0.911
F40H7.12
Uncharacterized protein.
      
 0.850
srh-217
Serpentine Receptor, class H.
      
 0.700
W09C3.8
Uncharacterized protein.
      
 0.698
F54E12.2
Uncharacterized protein.
      
 0.697
fbxb-59
FBA_2 domain-containing protein.
      
 0.692
fbxa-114
F-box domain-containing protein.
      
 0.660
Y113G7B.15
Uncharacterized protein; Belongs to the peptidase C1 family.
      
 0.636
fbxa-113
F-box domain-containing protein.
      
 0.614
mdt-17
Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
      
 0.580
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.