STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F41C3.5Serine carboxypeptidase ctsa-1.1; Belongs to the peptidase S10 family. (469 aa)    
Predicted Functional Partners:
F40A3.3
Phosphatidylethanolamine-binding protein homolog F40A3.3.
   
 
 0.459
asp-3
Aspartic protease 3; Aspartic protease (Probable). Part of the necrosis cell death pathway. Involved in neuronal cell degeneration. Involved in heat stress response.
   
 
 0.427
prdx-3
Probable peroxiredoxin prdx-3; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
   
 
 0.424
hsp-3
Heat shock 70 kDa protein C; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.
   
 
 0.421
upb-1
CN hydrolase domain-containing protein.
   
   0.417
bgal-2
Glyco_hydro_35 domain-containing protein; Belongs to the glycosyl hydrolase 35 family.
   
 
 0.414
bgal-1
Beta-galactosidase.
   
 
 0.414
spp-10
SaPosin-like Protein family.
   
  
 0.410
tfg-1
PB1 domain-containing protein.
   
   0.406
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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