STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
oac-29Acyl_transf_3 domain-containing protein. (658 aa)    
Predicted Functional Partners:
plr-1
Probable E3 ubiquitin-protein ligase plr-1; Probable E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled (By similarity). Acts on both canonical and non- canonical Wnt signaling pathway (By similarity). Plays a role in the migration and axon guidance of different neuronal cell types including CAN, HSN, AVK and AVG. Promotes the differentiation and regulates the anteroposterior polarity of AVG unpaired interneurons by sequestering the [...]
   
 
 0.726
col-71
Col_cuticle_N domain-containing protein.
    
 
 0.712
sptf-2
SP (Specificity Protein) Transcription Factor.
   
 
 0.705
F07A11.4
Ubiquitin carboxyl-terminal hydrolase.
    
 
 0.703
nspd-3
Nematode Specific Peptide family, group D.
      
 0.699
ugt-19
UDP-GlucuronosylTransferase.
      
 0.697
col-38
Col_cuticle_N domain-containing protein.
    
 
 0.684
col-101
Col_cuticle_N domain-containing protein.
    
 
 0.681
grl-10
Ground-like domain-containing protein.
   
  
 0.669
oac-31
NRF domain-containing protein.
      
 0.666
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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