STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
msra-1PMSR domain-containing protein. (207 aa)    
Predicted Functional Partners:
F44E2.6
Uncharacterized protein F44E2.6.
 
 
 0.965
trx-2
Probable thioredoxin-2; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
   
 
 0.887
Y73B6BL.12
Thioredoxin; Belongs to the thioredoxin family.
   
 
 0.783
trxr-2
Probable glutathione reductase 2; Maintains high levels of reduced glutathione in the cytosol.
  
  
 0.781
Y22D7AL.10
Uncharacterized protein; Belongs to the GroES chaperonin family.
  
 
 0.775
dhfr-1
Putative dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
     
 0.743
mtrr-1
Methionine synthase reductase; Involved in the reductive regeneration of cob(I)alamin cofactor required for the maintenance of methionine synthase in a functional state.
   
  
 0.736
suox-1
Cytochrome b5 heme-binding domain-containing protein.
  
  
 0.734
pmp-5
ABC transmembrane type-1 domain-containing protein.
   
  
 0.705
dnj-27
DNaJ domain (Prokaryotic heat shock protein).
   
 
 0.698
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.