STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fer-1Sperm vesicle fusion protein fer-1; Required for the fusion of the membranous organelles (MOs) with the plasma membrane, a process essential in spermiogenesis. (2034 aa)    
Predicted Functional Partners:
spe-10
Palmitoyltransferase spe-10; Involved in spermatogenesis, specifically in the morphogenesis of fibrous body-membranous organelles (FB-MO), which are Golgi-derived organelles used for transporting sperm-specific components, in spermatocytes and in their localization into budding spermatids. Required for the proper formation of spermatids and spermatozoa.
   
 
 0.883
snt-6
C2 domain-containing protein.
   
  
 0.824
snt-7
C2 domain-containing protein.
   
  
 0.821
rbc-2
RaBConnectin related.
      
 0.809
snt-4
SyNapTotagmin.
   
  
 0.808
spe-15
Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
  
 0.797
spe-9
Sperm transmembrane protein 9; Required for fertilization. May be required for cell adhesion and/or function as a signaling molecule.
   
  
 0.786
snt-3
SyNapTotagmin.
   
  
 0.782
snt-5
SyNapTotagmin.
   
  
 0.781
spe-38
Uncharacterized protein.
   
 
 0.776
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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