Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| asd-1 | ceh-39 | R74.5a.2 | T26C11.7.2 | RRM domain-containing protein. | Homeobox protein ceh-39; Probable DNA-binding regulatory protein involved in cell-fate specification; Belongs to the CUT homeobox family. | 0.891 |
| asd-1 | her-1 | R74.5a.2 | ZK287.8a.1 | RRM domain-containing protein. | Protein her-1; Dictates male development. Probably plays a direct role in cell signaling during C.elegans sex determination. Inhibits the function of tra-2a. | 0.536 |
| asd-1 | sdc-1 | R74.5a.2 | F52E10.1.1 | RRM domain-containing protein. | Zinc finger protein sdc-1; Embryonic transcription factor regulating downstream genes involved specifically in the sex determination and dosage compensation pathways, or regulating other genes involved in the coordinate control of both processes. Component of the SDC complex that functions in sex determination and in X chromosome dosage compensation specifically in hermaphrodite (XX) animals. Involved in the recruitment of the condensin I-like dosage compensation complex to the male sex-determining autosomal gene her-1, thereby contributing to its repression and initiating hermaphrodit [...] | 0.407 |
| asd-1 | sdc-2 | R74.5a.2 | C35C5.1.2 | RRM domain-containing protein. | Sex determination and dosage compensation protein sdc-2; Component of the SDC complex that functions in sex determination and in X chromosome dosage compensation specifically in hermaphrodite (XX) animals. Required for the recruitment of the condensin I-like dosage compensation complex to the male sex-determining autosomal gene her-1, thereby contributing to its repression and initiating hermaphrodite sexual development. Plays a central role in X-chromosome recognition and in the recruitment and assembly of the dosage compensation complex and the dosage compensation protein dpy-21 onto [...] | 0.665 |
| asd-1 | sea-1 | R74.5a.2 | F19B10.9.1 | RRM domain-containing protein. | T-box transcription factor 18; Probable transcriptional regulator involved in developmental processes. Activates xol-1 transcription, either directly or indirectly, establishing that xol-1 acts as the master regulator to integrate both X chromosome and autosomal signals to determine sexual fate. | 0.861 |
| asd-1 | sea-2 | R74.5a.2 | K10G6.3g.1 | RRM domain-containing protein. | C2H2-type domain-containing protein. | 0.855 |
| asd-1 | sex-1 | R74.5a.2 | F44A6.2.2 | RRM domain-containing protein. | Steroid hormone receptor family member cnr14; Belongs to the nuclear hormone receptor family. NR1 subfamily. | 0.832 |
| asd-1 | xol-1 | R74.5a.2 | C18A11.5c.1 | RRM domain-containing protein. | XO lethal protein 1; Acts as a primary sex-determining factor that promotes sexual differentiation. Absolutely required for proper sexual differentiation and male viability. High expression during gastrulation triggers male development, while low expression at that time triggers hermaphrodite development. Although related to GHMP kinase, its mode of action remains unclear; Belongs to the GHMP kinase family. Xol-1 subfamily. | 0.810 |
| ceh-39 | asd-1 | T26C11.7.2 | R74.5a.2 | Homeobox protein ceh-39; Probable DNA-binding regulatory protein involved in cell-fate specification; Belongs to the CUT homeobox family. | RRM domain-containing protein. | 0.891 |
| ceh-39 | fox-1 | T26C11.7.2 | T07D1.4d.1 | Homeobox protein ceh-39; Probable DNA-binding regulatory protein involved in cell-fate specification; Belongs to the CUT homeobox family. | Sex determination protein fox-1; A member of the sex determination pathway involved in making the distinction between one and two X-chromosomes. RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUG-3' elements. Regulates alternative splicing of tissue-specific exons. Promotes binding of sup-12 to target RNA. | 0.814 |
| ceh-39 | sdc-1 | T26C11.7.2 | F52E10.1.1 | Homeobox protein ceh-39; Probable DNA-binding regulatory protein involved in cell-fate specification; Belongs to the CUT homeobox family. | Zinc finger protein sdc-1; Embryonic transcription factor regulating downstream genes involved specifically in the sex determination and dosage compensation pathways, or regulating other genes involved in the coordinate control of both processes. Component of the SDC complex that functions in sex determination and in X chromosome dosage compensation specifically in hermaphrodite (XX) animals. Involved in the recruitment of the condensin I-like dosage compensation complex to the male sex-determining autosomal gene her-1, thereby contributing to its repression and initiating hermaphrodit [...] | 0.436 |
| ceh-39 | sdc-2 | T26C11.7.2 | C35C5.1.2 | Homeobox protein ceh-39; Probable DNA-binding regulatory protein involved in cell-fate specification; Belongs to the CUT homeobox family. | Sex determination and dosage compensation protein sdc-2; Component of the SDC complex that functions in sex determination and in X chromosome dosage compensation specifically in hermaphrodite (XX) animals. Required for the recruitment of the condensin I-like dosage compensation complex to the male sex-determining autosomal gene her-1, thereby contributing to its repression and initiating hermaphrodite sexual development. Plays a central role in X-chromosome recognition and in the recruitment and assembly of the dosage compensation complex and the dosage compensation protein dpy-21 onto [...] | 0.602 |
| ceh-39 | sea-1 | T26C11.7.2 | F19B10.9.1 | Homeobox protein ceh-39; Probable DNA-binding regulatory protein involved in cell-fate specification; Belongs to the CUT homeobox family. | T-box transcription factor 18; Probable transcriptional regulator involved in developmental processes. Activates xol-1 transcription, either directly or indirectly, establishing that xol-1 acts as the master regulator to integrate both X chromosome and autosomal signals to determine sexual fate. | 0.893 |
| ceh-39 | sea-2 | T26C11.7.2 | K10G6.3g.1 | Homeobox protein ceh-39; Probable DNA-binding regulatory protein involved in cell-fate specification; Belongs to the CUT homeobox family. | C2H2-type domain-containing protein. | 0.851 |
| ceh-39 | sex-1 | T26C11.7.2 | F44A6.2.2 | Homeobox protein ceh-39; Probable DNA-binding regulatory protein involved in cell-fate specification; Belongs to the CUT homeobox family. | Steroid hormone receptor family member cnr14; Belongs to the nuclear hormone receptor family. NR1 subfamily. | 0.852 |
| ceh-39 | xol-1 | T26C11.7.2 | C18A11.5c.1 | Homeobox protein ceh-39; Probable DNA-binding regulatory protein involved in cell-fate specification; Belongs to the CUT homeobox family. | XO lethal protein 1; Acts as a primary sex-determining factor that promotes sexual differentiation. Absolutely required for proper sexual differentiation and male viability. High expression during gastrulation triggers male development, while low expression at that time triggers hermaphrodite development. Although related to GHMP kinase, its mode of action remains unclear; Belongs to the GHMP kinase family. Xol-1 subfamily. | 0.857 |
| fox-1 | ceh-39 | T07D1.4d.1 | T26C11.7.2 | Sex determination protein fox-1; A member of the sex determination pathway involved in making the distinction between one and two X-chromosomes. RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUG-3' elements. Regulates alternative splicing of tissue-specific exons. Promotes binding of sup-12 to target RNA. | Homeobox protein ceh-39; Probable DNA-binding regulatory protein involved in cell-fate specification; Belongs to the CUT homeobox family. | 0.814 |
| fox-1 | her-1 | T07D1.4d.1 | ZK287.8a.1 | Sex determination protein fox-1; A member of the sex determination pathway involved in making the distinction between one and two X-chromosomes. RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUG-3' elements. Regulates alternative splicing of tissue-specific exons. Promotes binding of sup-12 to target RNA. | Protein her-1; Dictates male development. Probably plays a direct role in cell signaling during C.elegans sex determination. Inhibits the function of tra-2a. | 0.740 |
| fox-1 | sdc-1 | T07D1.4d.1 | F52E10.1.1 | Sex determination protein fox-1; A member of the sex determination pathway involved in making the distinction between one and two X-chromosomes. RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUG-3' elements. Regulates alternative splicing of tissue-specific exons. Promotes binding of sup-12 to target RNA. | Zinc finger protein sdc-1; Embryonic transcription factor regulating downstream genes involved specifically in the sex determination and dosage compensation pathways, or regulating other genes involved in the coordinate control of both processes. Component of the SDC complex that functions in sex determination and in X chromosome dosage compensation specifically in hermaphrodite (XX) animals. Involved in the recruitment of the condensin I-like dosage compensation complex to the male sex-determining autosomal gene her-1, thereby contributing to its repression and initiating hermaphrodit [...] | 0.738 |
| fox-1 | sdc-2 | T07D1.4d.1 | C35C5.1.2 | Sex determination protein fox-1; A member of the sex determination pathway involved in making the distinction between one and two X-chromosomes. RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUG-3' elements. Regulates alternative splicing of tissue-specific exons. Promotes binding of sup-12 to target RNA. | Sex determination and dosage compensation protein sdc-2; Component of the SDC complex that functions in sex determination and in X chromosome dosage compensation specifically in hermaphrodite (XX) animals. Required for the recruitment of the condensin I-like dosage compensation complex to the male sex-determining autosomal gene her-1, thereby contributing to its repression and initiating hermaphrodite sexual development. Plays a central role in X-chromosome recognition and in the recruitment and assembly of the dosage compensation complex and the dosage compensation protein dpy-21 onto [...] | 0.706 |
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