Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| F11E6.8 | T22A3.6 | F11E6.8a.1 | T22A3.6.1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. | Kringle domain-containing protein. | 0.806 |
| F11E6.8 | dep-1 | F11E6.8a.1 | F44G4.8a.1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. | Receptor-type tyrosine-protein phosphatase dep-1; Phosphatase which may dephosphorylate receptor let-23 and thereby regulate cell fate during the development of the vulva and the excretory system. By inhibiting let-23 signaling prevents the establishment of a primary cell fate in the descendants of vulva precursor cells P5.p and P7.p. Similarly, may prevent duct cell fate in ABpr precursor. Also dephosphorylates the beta-integrin subunit pat-3, probably within the alpha pat-2/beta pat-3 integrin receptor complex, which leads to down- stream effects including the negative regulation of [...] | 0.793 |
| F11E6.8 | let-23 | F11E6.8a.1 | ZK1067.1d.1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. | Receptor tyrosine-protein kinase let-23; Tyrosine-protein kinase receptor which, upon binding ligand lin-3, activates 2 signaling cascades: the let-60/Ras and MAP kinase signaling pathway and the let-60-independent phospholipase C-mediated Ca(2+) signaling pathway. Each pathway regulates distinct functions. By activating let-60/Ras, regulates larval development, induction of vulva cell precursors during vulva development, male spicule formation and posterior development of the epidermis. Probably by activating phospholipase plc-3 and inositol 1,4,5-trisphosphate receptor itr-1 signalin [...] | 0.598 |
| F11E6.8 | sli-1 | F11E6.8a.1 | M02A10.3a.1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. | Suppressor of LIneage defect. | 0.757 |
| F21F3.7 | T08G11.1 | F21F3.7.1 | T08G11.1a.1 | Uncharacterized protein. | Uncharacterized protein. | 0.921 |
| F21F3.7 | dep-1 | F21F3.7.1 | F44G4.8a.1 | Uncharacterized protein. | Receptor-type tyrosine-protein phosphatase dep-1; Phosphatase which may dephosphorylate receptor let-23 and thereby regulate cell fate during the development of the vulva and the excretory system. By inhibiting let-23 signaling prevents the establishment of a primary cell fate in the descendants of vulva precursor cells P5.p and P7.p. Similarly, may prevent duct cell fate in ABpr precursor. Also dephosphorylates the beta-integrin subunit pat-3, probably within the alpha pat-2/beta pat-3 integrin receptor complex, which leads to down- stream effects including the negative regulation of [...] | 0.821 |
| T08G11.1 | F21F3.7 | T08G11.1a.1 | F21F3.7.1 | Uncharacterized protein. | Uncharacterized protein. | 0.921 |
| T08G11.1 | dep-1 | T08G11.1a.1 | F44G4.8a.1 | Uncharacterized protein. | Receptor-type tyrosine-protein phosphatase dep-1; Phosphatase which may dephosphorylate receptor let-23 and thereby regulate cell fate during the development of the vulva and the excretory system. By inhibiting let-23 signaling prevents the establishment of a primary cell fate in the descendants of vulva precursor cells P5.p and P7.p. Similarly, may prevent duct cell fate in ABpr precursor. Also dephosphorylates the beta-integrin subunit pat-3, probably within the alpha pat-2/beta pat-3 integrin receptor complex, which leads to down- stream effects including the negative regulation of [...] | 0.672 |
| T22A3.6 | F11E6.8 | T22A3.6.1 | F11E6.8a.1 | Kringle domain-containing protein. | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. | 0.806 |
| T22A3.6 | dep-1 | T22A3.6.1 | F44G4.8a.1 | Kringle domain-containing protein. | Receptor-type tyrosine-protein phosphatase dep-1; Phosphatase which may dephosphorylate receptor let-23 and thereby regulate cell fate during the development of the vulva and the excretory system. By inhibiting let-23 signaling prevents the establishment of a primary cell fate in the descendants of vulva precursor cells P5.p and P7.p. Similarly, may prevent duct cell fate in ABpr precursor. Also dephosphorylates the beta-integrin subunit pat-3, probably within the alpha pat-2/beta pat-3 integrin receptor complex, which leads to down- stream effects including the negative regulation of [...] | 0.753 |
| T22A3.6 | let-23 | T22A3.6.1 | ZK1067.1d.1 | Kringle domain-containing protein. | Receptor tyrosine-protein kinase let-23; Tyrosine-protein kinase receptor which, upon binding ligand lin-3, activates 2 signaling cascades: the let-60/Ras and MAP kinase signaling pathway and the let-60-independent phospholipase C-mediated Ca(2+) signaling pathway. Each pathway regulates distinct functions. By activating let-60/Ras, regulates larval development, induction of vulva cell precursors during vulva development, male spicule formation and posterior development of the epidermis. Probably by activating phospholipase plc-3 and inositol 1,4,5-trisphosphate receptor itr-1 signalin [...] | 0.539 |
| T22A3.6 | sli-1 | T22A3.6.1 | M02A10.3a.1 | Kringle domain-containing protein. | Suppressor of LIneage defect. | 0.509 |
| ark-1 | dep-1 | C01C7.1a.1 | F44G4.8a.1 | Ack-related non-receptor tyrosine kinase; Probable tyrosine protein kinase which plays a role in vulva development, probably by acting as a negative regulator of the let- 23/EGFR and let-60/ras pathway. Involved in the negative regulation of germline development. | Receptor-type tyrosine-protein phosphatase dep-1; Phosphatase which may dephosphorylate receptor let-23 and thereby regulate cell fate during the development of the vulva and the excretory system. By inhibiting let-23 signaling prevents the establishment of a primary cell fate in the descendants of vulva precursor cells P5.p and P7.p. Similarly, may prevent duct cell fate in ABpr precursor. Also dephosphorylates the beta-integrin subunit pat-3, probably within the alpha pat-2/beta pat-3 integrin receptor complex, which leads to down- stream effects including the negative regulation of [...] | 0.679 |
| ark-1 | dpy-23 | C01C7.1a.1 | R160.1a.1 | Ack-related non-receptor tyrosine kinase; Probable tyrosine protein kinase which plays a role in vulva development, probably by acting as a negative regulator of the let- 23/EGFR and let-60/ras pathway. Involved in the negative regulation of germline development. | AP-2 complex subunit mu; Component of the adaptor complexes which link clathrin to receptors in coated vesicles (By similarity). Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (By similarity). AP50 is a subunit of the plasma membrane adaptor (By similarity). Essential wnt/egl-20 signaling protein that functions in wnt/egl-20-producing cells. Required for the AP-2 complex-mediated endocytosis of membrane proteins including wntless homolog mig-14 in egl-20-producing cells. During [...] | 0.699 |
| ark-1 | let-23 | C01C7.1a.1 | ZK1067.1d.1 | Ack-related non-receptor tyrosine kinase; Probable tyrosine protein kinase which plays a role in vulva development, probably by acting as a negative regulator of the let- 23/EGFR and let-60/ras pathway. Involved in the negative regulation of germline development. | Receptor tyrosine-protein kinase let-23; Tyrosine-protein kinase receptor which, upon binding ligand lin-3, activates 2 signaling cascades: the let-60/Ras and MAP kinase signaling pathway and the let-60-independent phospholipase C-mediated Ca(2+) signaling pathway. Each pathway regulates distinct functions. By activating let-60/Ras, regulates larval development, induction of vulva cell precursors during vulva development, male spicule formation and posterior development of the epidermis. Probably by activating phospholipase plc-3 and inositol 1,4,5-trisphosphate receptor itr-1 signalin [...] | 0.516 |
| ark-1 | lip-1 | C01C7.1a.1 | C05B10.1b.1 | Ack-related non-receptor tyrosine kinase; Probable tyrosine protein kinase which plays a role in vulva development, probably by acting as a negative regulator of the let- 23/EGFR and let-60/ras pathway. Involved in the negative regulation of germline development. | Dual specificity protein phosphatase lip-1; Dephosphorylates MAP kinase mpk-1. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | 0.824 |
| ark-1 | sli-1 | C01C7.1a.1 | M02A10.3a.1 | Ack-related non-receptor tyrosine kinase; Probable tyrosine protein kinase which plays a role in vulva development, probably by acting as a negative regulator of the let- 23/EGFR and let-60/ras pathway. Involved in the negative regulation of germline development. | Suppressor of LIneage defect. | 0.808 |
| dep-1 | F11E6.8 | F44G4.8a.1 | F11E6.8a.1 | Receptor-type tyrosine-protein phosphatase dep-1; Phosphatase which may dephosphorylate receptor let-23 and thereby regulate cell fate during the development of the vulva and the excretory system. By inhibiting let-23 signaling prevents the establishment of a primary cell fate in the descendants of vulva precursor cells P5.p and P7.p. Similarly, may prevent duct cell fate in ABpr precursor. Also dephosphorylates the beta-integrin subunit pat-3, probably within the alpha pat-2/beta pat-3 integrin receptor complex, which leads to down- stream effects including the negative regulation of [...] | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. | 0.793 |
| dep-1 | F21F3.7 | F44G4.8a.1 | F21F3.7.1 | Receptor-type tyrosine-protein phosphatase dep-1; Phosphatase which may dephosphorylate receptor let-23 and thereby regulate cell fate during the development of the vulva and the excretory system. By inhibiting let-23 signaling prevents the establishment of a primary cell fate in the descendants of vulva precursor cells P5.p and P7.p. Similarly, may prevent duct cell fate in ABpr precursor. Also dephosphorylates the beta-integrin subunit pat-3, probably within the alpha pat-2/beta pat-3 integrin receptor complex, which leads to down- stream effects including the negative regulation of [...] | Uncharacterized protein. | 0.821 |
| dep-1 | T08G11.1 | F44G4.8a.1 | T08G11.1a.1 | Receptor-type tyrosine-protein phosphatase dep-1; Phosphatase which may dephosphorylate receptor let-23 and thereby regulate cell fate during the development of the vulva and the excretory system. By inhibiting let-23 signaling prevents the establishment of a primary cell fate in the descendants of vulva precursor cells P5.p and P7.p. Similarly, may prevent duct cell fate in ABpr precursor. Also dephosphorylates the beta-integrin subunit pat-3, probably within the alpha pat-2/beta pat-3 integrin receptor complex, which leads to down- stream effects including the negative regulation of [...] | Uncharacterized protein. | 0.672 |
page 1 of 3