STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cla-1Protein clarinet; Required for synapse development in the active zone of presynaptic terminals of specific neurons including serotonergic NSM neurons. The active zone is a protein-dense neuronal region within the presynaptic bouton, from which synaptic vesicles send neurotransmitter signals across the synapse. Plays a role in the recruitment and clustering of synaptic vesicles in the active zone of presynaptic terminals in serotonergic NSM neurons, and coordinates the release of synaptic vesicles at presynaptic terminals to regulate neurotransmission at neuromuscular junctions. Regulat [...] (8922 aa)    
Predicted Functional Partners:
Y46B2A.3
Uncharacterized protein.
      
 0.811
clec-80
C-type lectin domain-containing protein.
      
 0.811
Y25C1A.7
Yip1 domain-containing protein.
      
 0.758
C11E4.6
Uncharacterized protein.
   
 
 0.735
H06I04.1
Uncharacterized protein.
    
 
 0.718
rimb-1
RIM Binding protein.
    
 
 0.709
elks-1
Mammalian ELKS/CAST/ERC/Rab6 interacting protein homolog.
   
 
 0.707
C03H5.6
BTB domain-containing protein.
    
 
 0.702
F21C10.7
Uncharacterized protein.
   
 
 0.698
znf-207
BED-type domain-containing protein.
      
 0.697
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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