node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F45G2.10 | F45G2.8 | F45G2.10.1 | F45G2.8.1 | MIP18 family protein F45G2.10; May play a role in chromosome segregation through establishment of sister chromatid cohesion; Belongs to the MIP18 family. | Mitochondrial import inner membrane translocase subunit tim-16; Regulates ATP-dependent protein translocation into the mitochondrial matrix; Belongs to the TIM16/PAM16 family. | 0.568 |
F45G2.10 | F45G2.9 | F45G2.10.1 | F45G2.9.1 | MIP18 family protein F45G2.10; May play a role in chromosome segregation through establishment of sister chromatid cohesion; Belongs to the MIP18 family. | rRNA methyltransferase 2, mitochondrial; S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methyluridine at position 808 (Um808) in the mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA. | 0.907 |
F45G2.10 | T20B12.7 | F45G2.10.1 | T20B12.7.1 | MIP18 family protein F45G2.10; May play a role in chromosome segregation through establishment of sister chromatid cohesion; Belongs to the MIP18 family. | Anamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...] | 0.673 |
F45G2.10 | Y18D10A.9 | F45G2.10.1 | Y18D10A.9.1 | MIP18 family protein F45G2.10; May play a role in chromosome segregation through establishment of sister chromatid cohesion; Belongs to the MIP18 family. | Probable cytosolic iron-sulfur protein assembly protein CIAO1 homolog; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins; Belongs to the WD repeat CIA1 family. | 0.996 |
F45G2.10 | eif-3.L | F45G2.10.1 | C17G10.9e.1 | MIP18 family protein F45G2.10; May play a role in chromosome segregation through establishment of sister chromatid cohesion; Belongs to the MIP18 family. | Eukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. | 0.653 |
F45G2.10 | fre-1 | F45G2.10.1 | Y113G7A.8b.1 | MIP18 family protein F45G2.10; May play a role in chromosome segregation through establishment of sister chromatid cohesion; Belongs to the MIP18 family. | NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe-S cluster of the anamorsin/DRE2 homolog. Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family. In the N-terminal section; belongs to the flavodoxin family. | 0.686 |
F45G2.10 | mms-19 | F45G2.10.1 | C24G6.3.1 | MIP18 family protein F45G2.10; May play a role in chromosome segregation through establishment of sister chromatid cohesion; Belongs to the MIP18 family. | MMS19_N domain-containing protein. | 0.984 |
F45G2.10 | nubp-1 | F45G2.10.1 | F10G8.6.1 | MIP18 family protein F45G2.10; May play a role in chromosome segregation through establishment of sister chromatid cohesion; Belongs to the MIP18 family. | Cytosolic Fe-S cluster assembly factor NUBP1 homolog; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins (By similarity). Regulates cilium formation and structure ; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | 0.699 |
F45G2.10 | oxy-4 | F45G2.10.1 | Y54H5A.4.1 | MIP18 family protein F45G2.10; May play a role in chromosome segregation through establishment of sister chromatid cohesion; Belongs to the MIP18 family. | Probable cytosolic Fe-S cluster assembly factor oxy-4; Component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins (By similarity); Belongs to the NARF family. | 0.940 |
F45G2.10 | xpd-1 | F45G2.10.1 | Y50D7A.2.1 | MIP18 family protein F45G2.10; May play a role in chromosome segregation through establishment of sister chromatid cohesion; Belongs to the MIP18 family. | Helicase ATP-binding domain-containing protein. | 0.848 |
F45G2.8 | F45G2.10 | F45G2.8.1 | F45G2.10.1 | Mitochondrial import inner membrane translocase subunit tim-16; Regulates ATP-dependent protein translocation into the mitochondrial matrix; Belongs to the TIM16/PAM16 family. | MIP18 family protein F45G2.10; May play a role in chromosome segregation through establishment of sister chromatid cohesion; Belongs to the MIP18 family. | 0.568 |
F45G2.8 | fre-1 | F45G2.8.1 | Y113G7A.8b.1 | Mitochondrial import inner membrane translocase subunit tim-16; Regulates ATP-dependent protein translocation into the mitochondrial matrix; Belongs to the TIM16/PAM16 family. | NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe-S cluster of the anamorsin/DRE2 homolog. Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family. In the N-terminal section; belongs to the flavodoxin family. | 0.668 |
F45G2.9 | F45G2.10 | F45G2.9.1 | F45G2.10.1 | rRNA methyltransferase 2, mitochondrial; S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methyluridine at position 808 (Um808) in the mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA. | MIP18 family protein F45G2.10; May play a role in chromosome segregation through establishment of sister chromatid cohesion; Belongs to the MIP18 family. | 0.907 |
T20B12.7 | F45G2.10 | T20B12.7.1 | F45G2.10.1 | Anamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...] | MIP18 family protein F45G2.10; May play a role in chromosome segregation through establishment of sister chromatid cohesion; Belongs to the MIP18 family. | 0.673 |
T20B12.7 | Y18D10A.9 | T20B12.7.1 | Y18D10A.9.1 | Anamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...] | Probable cytosolic iron-sulfur protein assembly protein CIAO1 homolog; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins; Belongs to the WD repeat CIA1 family. | 0.671 |
T20B12.7 | fre-1 | T20B12.7.1 | Y113G7A.8b.1 | Anamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...] | NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe-S cluster of the anamorsin/DRE2 homolog. Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family. In the N-terminal section; belongs to the flavodoxin family. | 0.962 |
T20B12.7 | mms-19 | T20B12.7.1 | C24G6.3.1 | Anamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...] | MMS19_N domain-containing protein. | 0.672 |
T20B12.7 | nubp-1 | T20B12.7.1 | F10G8.6.1 | Anamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...] | Cytosolic Fe-S cluster assembly factor NUBP1 homolog; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins (By similarity). Regulates cilium formation and structure ; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | 0.765 |
T20B12.7 | oxy-4 | T20B12.7.1 | Y54H5A.4.1 | Anamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...] | Probable cytosolic Fe-S cluster assembly factor oxy-4; Component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins (By similarity); Belongs to the NARF family. | 0.727 |
Y18D10A.9 | F45G2.10 | Y18D10A.9.1 | F45G2.10.1 | Probable cytosolic iron-sulfur protein assembly protein CIAO1 homolog; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins; Belongs to the WD repeat CIA1 family. | MIP18 family protein F45G2.10; May play a role in chromosome segregation through establishment of sister chromatid cohesion; Belongs to the MIP18 family. | 0.996 |