STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mgl-2G_PROTEIN_RECEP_F3_4 domain-containing protein. (1035 aa)    
Predicted Functional Partners:
egl-30
Heterotrimeric G protein alpha subunit.
   
 0.913
F35H10.10
G_PROTEIN_RECEP_F3_4 domain-containing protein; Belongs to the G-protein coupled receptor 3 family.
   
 
 
0.802
glr-1
Glutamate receptor 1; Non-NMDA (N-methyl-D-aspartate) ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of glutamate are mediated by a variety of receptors that are named according to their selective agonists. May contribute to a sensory discrimination between mechanical and chemical stimuli. Plays a role in controlling movement in response to environmental cues such as food availability and mechanosensory stimulation such as the nose touch response. In AIB interneurons, promotes om [...]
   
  
 0.768
gpb-2
Guanine nucleotide-binding protein subunit beta-2; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
 0.733
tbc-16
Rab-GAP TBC domain-containing protein.
   
  
 0.704
Y39G8C.2
Protein kinase domain-containing protein.
      
 0.697
nmr-2
NMDA-type ionotropic glutamate receptor NMR-2.
   
 
 0.691
pef-1
Serine/threonine-protein phosphatase with EF-hands pef-1; Probably acts as a protein phosphatase.
   
  
 0.676
pcrg-1
Parkin Co-Regulated Gene (PACRG) homolog.
   
 
 0.668
mgl-3
G_PROTEIN_RECEP_F3_4 domain-containing protein.
  
 
0.654
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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