STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lact-1Beta-lactamase domain-containing protein. (393 aa)    
Predicted Functional Partners:
hex-1
Beta-hexosaminidase A; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines. Degrades chitotriose.
    
  0.813
T19B10.2
Uncharacterized protein.
      
 0.808
R09B5.11
Facilitated glucose transporter homolog; Appears to have no transport activity for glucose.
  
  
 0.786
chat-1
CDC50 family protein chat-1; Probable chaperone protein for the phospholipid-transporting ATPase tat-1. Regulates cell membrane structure and function. Plays a role in maintaining the membrane phosphatidylserine asymmetry and the formation of the tubular membrane structure. Involved in membrane trafficking and is specifically involved in the recycling and degradation of endocytic cargo and this is likely with the phospholipid-transporting ATPase tat-1.
      
 0.690
grsp-2
Glycine Rich Secreted Protein.
      
 0.667
far-3
Fatty Acid/Retinol binding protein.
      
 0.663
str-83
Seven TM Receptor.
      
 0.660
srx-62
G_PROTEIN_RECEP_F1_2 domain-containing protein.
      
 0.660
glod-4
Glyoxalase 1; Thought to act as a glyoxalase. May remove methylglyoxal from mitochondrial proteins. Has roles in reducing oxidative stress and increasing lifespan.
  
 
 0.631
mce-1
Mitochondrial methylmalonyl-CoA epimerase.
  
 
 0.631
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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