STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F47B8.4Glutaredoxin domain-containing protein. (282 aa)    
Predicted Functional Partners:
K10D11.2
CUB_2 domain-containing protein.
   
  
 0.812
ZK896.5
CUB_2 domain-containing protein.
      
 0.810
T20B12.7
Anamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...]
    
 
 0.776
W01A11.1
Epoxide hydrolase.
      
 0.739
K11H12.1
Putative bolA-like protein K11H12.1; Belongs to the BolA/IbaG family.
  
 
 0.714
T12D8.10
Uncharacterized protein; Belongs to the BolA/IbaG family.
  
 
 0.666
Y105E8A.11
Uncharacterized protein; Belongs to the BolA/IbaG family.
  
 
 0.666
H20E11.2
CUB_2 domain-containing protein.
      
 0.541
ssu-2
Suppressor of Stomatin mutant Uncoordination.
      
 0.531
lpd-8
Nfu_N domain-containing protein.
   
  
 0.491
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.