node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C05C8.5 | C08B6.8 | C05C8.5.1 | C08B6.8a.1 | Exonuclease domain-containing protein. | Probable oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides. | 0.947 |
C05C8.5 | Y56A3A.33 | C05C8.5.1 | Y56A3A.33.1 | Exonuclease domain-containing protein. | Exonuclease domain-containing protein. | 0.910 |
C05C8.5 | crn-3 | C05C8.5.1 | C14A4.4a.1 | Exonuclease domain-containing protein. | HRDC domain-containing protein. | 0.604 |
C05C8.5 | panl-3 | C05C8.5.1 | ZK632.7.1 | Exonuclease domain-containing protein. | PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] | 0.718 |
C05C8.5 | pcn-1 | C05C8.5.1 | W03D2.4.1 | Exonuclease domain-containing protein. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.784 |
C05C8.5 | pqe-1 | C05C8.5.1 | F52C9.8b.1 | Exonuclease domain-containing protein. | Putative RNA exonuclease pqe-1; Putative RNA exonuclease which protects neurons from the toxic effects of expanded poly-Q disease proteins. It is unknown whether this is via participation in the pathogenic mechanism underlying poly-Q-induced neurodegeneration or if it is by acting as a genetic modifier of the age of onset or progression of neurodegeneration. Regulates gene expression in neurons. | 0.905 |
C08B6.8 | C05C8.5 | C08B6.8a.1 | C05C8.5.1 | Probable oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides. | Exonuclease domain-containing protein. | 0.947 |
C08B6.8 | Y56A3A.33 | C08B6.8a.1 | Y56A3A.33.1 | Probable oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides. | Exonuclease domain-containing protein. | 0.943 |
C08B6.8 | crn-3 | C08B6.8a.1 | C14A4.4a.1 | Probable oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides. | HRDC domain-containing protein. | 0.708 |
C08B6.8 | pqe-1 | C08B6.8a.1 | F52C9.8b.1 | Probable oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides. | Putative RNA exonuclease pqe-1; Putative RNA exonuclease which protects neurons from the toxic effects of expanded poly-Q disease proteins. It is unknown whether this is via participation in the pathogenic mechanism underlying poly-Q-induced neurodegeneration or if it is by acting as a genetic modifier of the age of onset or progression of neurodegeneration. Regulates gene expression in neurons. | 0.943 |
F02E9.10 | crn-3 | F02E9.10c.1 | C14A4.4a.1 | WD_REPEATS_REGION domain-containing protein. | HRDC domain-containing protein. | 0.558 |
F02E9.10 | pqe-1 | F02E9.10c.1 | F52C9.8b.1 | WD_REPEATS_REGION domain-containing protein. | Putative RNA exonuclease pqe-1; Putative RNA exonuclease which protects neurons from the toxic effects of expanded poly-Q disease proteins. It is unknown whether this is via participation in the pathogenic mechanism underlying poly-Q-induced neurodegeneration or if it is by acting as a genetic modifier of the age of onset or progression of neurodegeneration. Regulates gene expression in neurons. | 0.539 |
Y56A3A.33 | C05C8.5 | Y56A3A.33.1 | C05C8.5.1 | Exonuclease domain-containing protein. | Exonuclease domain-containing protein. | 0.910 |
Y56A3A.33 | C08B6.8 | Y56A3A.33.1 | C08B6.8a.1 | Exonuclease domain-containing protein. | Probable oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides. | 0.943 |
Y56A3A.33 | crn-3 | Y56A3A.33.1 | C14A4.4a.1 | Exonuclease domain-containing protein. | HRDC domain-containing protein. | 0.585 |
Y56A3A.33 | panl-3 | Y56A3A.33.1 | ZK632.7.1 | Exonuclease domain-containing protein. | PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] | 0.713 |
Y56A3A.33 | pcn-1 | Y56A3A.33.1 | W03D2.4.1 | Exonuclease domain-containing protein. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.771 |
Y56A3A.33 | pqe-1 | Y56A3A.33.1 | F52C9.8b.1 | Exonuclease domain-containing protein. | Putative RNA exonuclease pqe-1; Putative RNA exonuclease which protects neurons from the toxic effects of expanded poly-Q disease proteins. It is unknown whether this is via participation in the pathogenic mechanism underlying poly-Q-induced neurodegeneration or if it is by acting as a genetic modifier of the age of onset or progression of neurodegeneration. Regulates gene expression in neurons. | 0.900 |
crn-3 | C05C8.5 | C14A4.4a.1 | C05C8.5.1 | HRDC domain-containing protein. | Exonuclease domain-containing protein. | 0.604 |
crn-3 | C08B6.8 | C14A4.4a.1 | C08B6.8a.1 | HRDC domain-containing protein. | Probable oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides. | 0.708 |