STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bcs-1BCS1 (Mitochondrial chaperone) homolog; Belongs to the AAA ATPase family. (442 aa)    
Predicted Functional Partners:
pinn-4
Peptidyl-prolyl cis-trans isomerase.
  
  
 0.822
Y57A10A.29
Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer; Belongs to the SDHAF2 family.
  
  
 0.818
zipt-7.2
Zinc transporter zipt-7.2; Zinc transporter.
 
 
    0.807
C35D10.5
Uncharacterized protein.
   
  
 0.786
phip-1
Protein HIstidine Phosphatase.
   
  
 0.782
mrpl-16
Ribosomal_L16 domain-containing protein.
   
 
 0.769
cpin-1
Amidohydro-rel domain-containing protein.
     
 0.768
cua-1
Copper transporting ATPase.
  
  
 0.767
fars-1
AA_TRNA_LIGASE_II domain-containing protein.
 
  
 0.737
mrps-16
Probable 28S ribosomal protein S16, mitochondrial; Belongs to the bacterial ribosomal protein bS16 family.
  
 
 0.726
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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