node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C56G2.5 | F55C10.5 | C56G2.5.1 | F55C10.5.1 | Non-specific serine/threonine protein kinase. | Uncharacterized protein. | 0.520 |
C56G2.5 | W04B5.5 | C56G2.5.1 | W04B5.5.1 | Non-specific serine/threonine protein kinase. | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | 0.595 |
C56G2.5 | ced-10 | C56G2.5.1 | C09G12.8b.1 | Non-specific serine/threonine protein kinase. | Ras-related protein ced-10; Required in engulfing to control the phagocytosis of apoptotic cell corpses. Required in embryonic development for the correct positioning and orientation of the mitotic spindles and division planes in blastomere cells. Involved in hypodermal cell fusion, together with pak-1 and cdc-42, leading to embryonic body elongation, which involves dramatic cytoskeletal reorganization. ced-2 and ced-5 function to activate ced-10 in a GTPase signaling pathway that controls the polarized extension of cell surfaces. Plays a redundant role with mig-2 in dorsal axonal guid [...] | 0.760 |
C56G2.5 | rho-1 | C56G2.5.1 | Y51H4A.3a.1 | Non-specific serine/threonine protein kinase. | Ras-like GTP-binding protein rhoA; Required for ventral migration of epidermal cells during ventral enclosure in the embryo and for cell elongation. Also required for ventral migration of P cells during larval development. Involved in asymmetric spindle positioning during anaphase and establishment of cell polarity during embryo development. In adults, involved in regulation of multiple processes including locomotion, pharyngeal pumping, fecundity, ovulation, defecation and body morphology. In body wall muscles, regulates organization of myosin thick filaments downstream of unc-89. Ass [...] | 0.760 |
F55C10.5 | C56G2.5 | F55C10.5.1 | C56G2.5.1 | Uncharacterized protein. | Non-specific serine/threonine protein kinase. | 0.520 |
F55C10.5 | W04B5.5 | F55C10.5.1 | W04B5.5.1 | Uncharacterized protein. | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | 0.499 |
F55C10.5 | ced-10 | F55C10.5.1 | C09G12.8b.1 | Uncharacterized protein. | Ras-related protein ced-10; Required in engulfing to control the phagocytosis of apoptotic cell corpses. Required in embryonic development for the correct positioning and orientation of the mitotic spindles and division planes in blastomere cells. Involved in hypodermal cell fusion, together with pak-1 and cdc-42, leading to embryonic body elongation, which involves dramatic cytoskeletal reorganization. ced-2 and ced-5 function to activate ced-10 in a GTPase signaling pathway that controls the polarized extension of cell surfaces. Plays a redundant role with mig-2 in dorsal axonal guid [...] | 0.517 |
F55C10.5 | gsp-1 | F55C10.5.1 | F29F11.6.1 | Uncharacterized protein. | Serine/threonine-protein phosphatase PP1-alpha; Serine/threonine-protein phosphatase which antagonizes the function of air-2 in the regulation of chromosome cohesion. Dephosphorylates histone H3 at 'Ser-10'. Dephosphorylates translation initiation factor eIF2alpha. Involved in the activation of chloride channel clh-3 during cell swelling and meiotic maturation. Belongs to the PPP phosphatase family. PP-1 subfamily. | 0.554 |
F55C10.5 | mei-1 | F55C10.5.1 | T01G9.5b.1 | Uncharacterized protein. | Meiotic spindle formation protein mei-1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays. Required specifically for meiotic spindle formation in the female germline; the presence of this protein is inimical to the formation of mitotic spindles. In body wall muscles, regulates organization of myosin thick filaments. | 0.430 |
F55C10.5 | mel-11 | F55C10.5.1 | C06C3.1c.1 | Uncharacterized protein. | ANK_REP_REGION domain-containing protein. | 0.546 |
F55C10.5 | pcm-1 | F55C10.5.1 | C10F3.5a.1 | Uncharacterized protein. | Protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. This enzyme does not act on D-aspartyl residues. | 0.431 |
F55C10.5 | rho-1 | F55C10.5.1 | Y51H4A.3a.1 | Uncharacterized protein. | Ras-like GTP-binding protein rhoA; Required for ventral migration of epidermal cells during ventral enclosure in the embryo and for cell elongation. Also required for ventral migration of P cells during larval development. Involved in asymmetric spindle positioning during anaphase and establishment of cell polarity during embryo development. In adults, involved in regulation of multiple processes including locomotion, pharyngeal pumping, fecundity, ovulation, defecation and body morphology. In body wall muscles, regulates organization of myosin thick filaments downstream of unc-89. Ass [...] | 0.517 |
F55C10.5 | sup-18 | F55C10.5.1 | C02C2.5.1 | Uncharacterized protein. | Iodotyrosine dehalogenase 1 homolog; May contribute to coordination of muscle contraction as regulatory subunit of the nonessential sup-9 potassium channel complex. May act downstream of sup-10. | 0.559 |
W04B5.5 | C56G2.5 | W04B5.5.1 | C56G2.5.1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | Non-specific serine/threonine protein kinase. | 0.595 |
W04B5.5 | F55C10.5 | W04B5.5.1 | F55C10.5.1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | Uncharacterized protein. | 0.499 |
W04B5.5 | ced-10 | W04B5.5.1 | C09G12.8b.1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | Ras-related protein ced-10; Required in engulfing to control the phagocytosis of apoptotic cell corpses. Required in embryonic development for the correct positioning and orientation of the mitotic spindles and division planes in blastomere cells. Involved in hypodermal cell fusion, together with pak-1 and cdc-42, leading to embryonic body elongation, which involves dramatic cytoskeletal reorganization. ced-2 and ced-5 function to activate ced-10 in a GTPase signaling pathway that controls the polarized extension of cell surfaces. Plays a redundant role with mig-2 in dorsal axonal guid [...] | 0.553 |
W04B5.5 | rho-1 | W04B5.5.1 | Y51H4A.3a.1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | Ras-like GTP-binding protein rhoA; Required for ventral migration of epidermal cells during ventral enclosure in the embryo and for cell elongation. Also required for ventral migration of P cells during larval development. Involved in asymmetric spindle positioning during anaphase and establishment of cell polarity during embryo development. In adults, involved in regulation of multiple processes including locomotion, pharyngeal pumping, fecundity, ovulation, defecation and body morphology. In body wall muscles, regulates organization of myosin thick filaments downstream of unc-89. Ass [...] | 0.600 |
ced-10 | C56G2.5 | C09G12.8b.1 | C56G2.5.1 | Ras-related protein ced-10; Required in engulfing to control the phagocytosis of apoptotic cell corpses. Required in embryonic development for the correct positioning and orientation of the mitotic spindles and division planes in blastomere cells. Involved in hypodermal cell fusion, together with pak-1 and cdc-42, leading to embryonic body elongation, which involves dramatic cytoskeletal reorganization. ced-2 and ced-5 function to activate ced-10 in a GTPase signaling pathway that controls the polarized extension of cell surfaces. Plays a redundant role with mig-2 in dorsal axonal guid [...] | Non-specific serine/threonine protein kinase. | 0.760 |
ced-10 | F55C10.5 | C09G12.8b.1 | F55C10.5.1 | Ras-related protein ced-10; Required in engulfing to control the phagocytosis of apoptotic cell corpses. Required in embryonic development for the correct positioning and orientation of the mitotic spindles and division planes in blastomere cells. Involved in hypodermal cell fusion, together with pak-1 and cdc-42, leading to embryonic body elongation, which involves dramatic cytoskeletal reorganization. ced-2 and ced-5 function to activate ced-10 in a GTPase signaling pathway that controls the polarized extension of cell surfaces. Plays a redundant role with mig-2 in dorsal axonal guid [...] | Uncharacterized protein. | 0.517 |
ced-10 | W04B5.5 | C09G12.8b.1 | W04B5.5.1 | Ras-related protein ced-10; Required in engulfing to control the phagocytosis of apoptotic cell corpses. Required in embryonic development for the correct positioning and orientation of the mitotic spindles and division planes in blastomere cells. Involved in hypodermal cell fusion, together with pak-1 and cdc-42, leading to embryonic body elongation, which involves dramatic cytoskeletal reorganization. ced-2 and ced-5 function to activate ced-10 in a GTPase signaling pathway that controls the polarized extension of cell surfaces. Plays a redundant role with mig-2 in dorsal axonal guid [...] | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | 0.553 |