STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F57A8.6DX domain-containing protein. (385 aa)    
Predicted Functional Partners:
C48B6.4
Tyrosine-protein phosphatase domain-containing protein.
   
    0.538
W09C3.2
Uncharacterized protein.
   
    0.537
C47E12.11
Uncharacterized protein.
   
    0.519
fbxa-202
F-box domain-containing protein.
   
    0.518
acs-18
AMP-binding domain-containing protein.
   
    0.513
C54D10.4
Uncharacterized protein; Belongs to the tetraspanin (TM4SF) family.
   
    0.502
ZK354.6
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
    0.482
F13A7.7
Uncharacterized protein.
   
    0.478
F31E8.5
Uncharacterized protein.
   
    0.468
ZC581.2
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
    0.463
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.