STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mei-2Meiotic spindle formation protein 2; Forms a heterodimeric complex in conjunction with mei-1 which severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. May act to target mei-1 within the cell. Required specifically for meiotic spindle formation in the female germline. (280 aa)    
Predicted Functional Partners:
C37C3.9
BTB domain-containing protein.
   
    0.999
F14H3.6
Uncharacterized protein.
   
    0.999
trcs-1
TRansport of membrane to Cell Surface.
   
    0.999
pos-1
Cytoplasmic zinc-finger protein.
   
    0.999
mei-1
Meiotic spindle formation protein mei-1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays. Required specifically for meiotic spindle formation in the female germline; the presence of this protein is inimical to the formation of mitotic spindles. In body wall muscles, regulates organization of myosin thick filaments.
   
 0.999
rme-2
Receptor Mediated Endocytosis.
   
    0.999
T22D1.5
Uncharacterized protein.
   
    0.999
spn-4
RRM domain-containing protein.
   
    0.999
gna-2
Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily.
   
    0.984
F18A1.7
CPG4 domain-containing protein.
   
    0.978
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.