node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
elt-1 | elt-6 | W09C2.1a.1 | F52C12.5.2 | Transcription factor elt-1; Transcriptional activator that binds to the consensus sequence 5'-[AT]GATA[AG]-3' and variations thereof. During embryonic development, required for specification of cell fate of major hypodermal (epidermal) cells at the blastomere stage. The requirement is true for all four lineages derived from ABarp, ABpra and C blastomeres. Required for seam cell maintenance in late embryogenesis, for proper formation of dauer larvae and locomotion. Regulates expression of bro-1, a regulator of seam cell proliferation, via a GATA-like binding motif. Probably represses ex [...] | GATA-like transcription factor ELT-6. | 0.730 |
elt-1 | end-3 | W09C2.1a.1 | F58E10.5.1 | Transcription factor elt-1; Transcriptional activator that binds to the consensus sequence 5'-[AT]GATA[AG]-3' and variations thereof. During embryonic development, required for specification of cell fate of major hypodermal (epidermal) cells at the blastomere stage. The requirement is true for all four lineages derived from ABarp, ABpra and C blastomeres. Required for seam cell maintenance in late embryogenesis, for proper formation of dauer larvae and locomotion. Regulates expression of bro-1, a regulator of seam cell proliferation, via a GATA-like binding motif. Probably represses ex [...] | GATA-type domain-containing protein. | 0.827 |
elt-1 | med-1 | W09C2.1a.1 | T24D3.1.1 | Transcription factor elt-1; Transcriptional activator that binds to the consensus sequence 5'-[AT]GATA[AG]-3' and variations thereof. During embryonic development, required for specification of cell fate of major hypodermal (epidermal) cells at the blastomere stage. The requirement is true for all four lineages derived from ABarp, ABpra and C blastomeres. Required for seam cell maintenance in late embryogenesis, for proper formation of dauer larvae and locomotion. Regulates expression of bro-1, a regulator of seam cell proliferation, via a GATA-like binding motif. Probably represses ex [...] | GATA-type domain-containing protein. | 0.787 |
elt-1 | med-2 | W09C2.1a.1 | K04C2.6.1 | Transcription factor elt-1; Transcriptional activator that binds to the consensus sequence 5'-[AT]GATA[AG]-3' and variations thereof. During embryonic development, required for specification of cell fate of major hypodermal (epidermal) cells at the blastomere stage. The requirement is true for all four lineages derived from ABarp, ABpra and C blastomeres. Required for seam cell maintenance in late embryogenesis, for proper formation of dauer larvae and locomotion. Regulates expression of bro-1, a regulator of seam cell proliferation, via a GATA-like binding motif. Probably represses ex [...] | GATA-type domain-containing protein. | 0.759 |
elt-1 | pha-4 | W09C2.1a.1 | F38A6.1a.1 | Transcription factor elt-1; Transcriptional activator that binds to the consensus sequence 5'-[AT]GATA[AG]-3' and variations thereof. During embryonic development, required for specification of cell fate of major hypodermal (epidermal) cells at the blastomere stage. The requirement is true for all four lineages derived from ABarp, ABpra and C blastomeres. Required for seam cell maintenance in late embryogenesis, for proper formation of dauer larvae and locomotion. Regulates expression of bro-1, a regulator of seam cell proliferation, via a GATA-like binding motif. Probably represses ex [...] | Defective pharyngeal development protein 4; Acts as a transcription factor required for formation of the pharyngeal primordium. Binds to the consensus sequence 5'-T[AG]TT[TG][AG][TC]-3' with variations of the sequence affecting onset of target gene expression. Activates a wide array of pharyngeal genes including ceh-22 and myo-2 and represses ectodermal genes lin-26 and elt-3, ensuring pharyngeal cell fate. Required for recruitment of htz-1 to a subset of pharyngeal promoters to ensure gene activation and also acts synergistically with tbx-2 in pharyngeal development. Acts in the regul [...] | 0.795 |
elt-1 | pop-1 | W09C2.1a.1 | W10C8.2.1 | Transcription factor elt-1; Transcriptional activator that binds to the consensus sequence 5'-[AT]GATA[AG]-3' and variations thereof. During embryonic development, required for specification of cell fate of major hypodermal (epidermal) cells at the blastomere stage. The requirement is true for all four lineages derived from ABarp, ABpra and C blastomeres. Required for seam cell maintenance in late embryogenesis, for proper formation of dauer larvae and locomotion. Regulates expression of bro-1, a regulator of seam cell proliferation, via a GATA-like binding motif. Probably represses ex [...] | Protein pop-1; Part of the Wnt signaling pathway essential for the specification of the mesodermal cell fate in early embryos. Required for asymmetrical division of somatic gonadal precursor descendants which initiate axis formation required to control organ shape. Represses expression of target genes via its interaction with hda-1 histone deacetylase. Required for specification of the M lineage-derived coelomocyte and sex myoblast fate. Regulates coelomocyte fate by positively regulating proliferation and ceh-34 and possibly eya-1 expression in M.dlpa and M.drpa precursors. | 0.489 |
elt-4 | end-3 | C39B10.6a.1 | F58E10.5.1 | GATA-type domain-containing protein. | GATA-type domain-containing protein. | 0.891 |
elt-4 | med-1 | C39B10.6a.1 | T24D3.1.1 | GATA-type domain-containing protein. | GATA-type domain-containing protein. | 0.758 |
elt-4 | med-2 | C39B10.6a.1 | K04C2.6.1 | GATA-type domain-containing protein. | GATA-type domain-containing protein. | 0.807 |
elt-4 | pha-4 | C39B10.6a.1 | F38A6.1a.1 | GATA-type domain-containing protein. | Defective pharyngeal development protein 4; Acts as a transcription factor required for formation of the pharyngeal primordium. Binds to the consensus sequence 5'-T[AG]TT[TG][AG][TC]-3' with variations of the sequence affecting onset of target gene expression. Activates a wide array of pharyngeal genes including ceh-22 and myo-2 and represses ectodermal genes lin-26 and elt-3, ensuring pharyngeal cell fate. Required for recruitment of htz-1 to a subset of pharyngeal promoters to ensure gene activation and also acts synergistically with tbx-2 in pharyngeal development. Acts in the regul [...] | 0.658 |
elt-6 | elt-1 | F52C12.5.2 | W09C2.1a.1 | GATA-like transcription factor ELT-6. | Transcription factor elt-1; Transcriptional activator that binds to the consensus sequence 5'-[AT]GATA[AG]-3' and variations thereof. During embryonic development, required for specification of cell fate of major hypodermal (epidermal) cells at the blastomere stage. The requirement is true for all four lineages derived from ABarp, ABpra and C blastomeres. Required for seam cell maintenance in late embryogenesis, for proper formation of dauer larvae and locomotion. Regulates expression of bro-1, a regulator of seam cell proliferation, via a GATA-like binding motif. Probably represses ex [...] | 0.730 |
elt-6 | end-3 | F52C12.5.2 | F58E10.5.1 | GATA-like transcription factor ELT-6. | GATA-type domain-containing protein. | 0.825 |
elt-6 | med-1 | F52C12.5.2 | T24D3.1.1 | GATA-like transcription factor ELT-6. | GATA-type domain-containing protein. | 0.791 |
elt-6 | med-2 | F52C12.5.2 | K04C2.6.1 | GATA-like transcription factor ELT-6. | GATA-type domain-containing protein. | 0.737 |
elt-6 | pha-4 | F52C12.5.2 | F38A6.1a.1 | GATA-like transcription factor ELT-6. | Defective pharyngeal development protein 4; Acts as a transcription factor required for formation of the pharyngeal primordium. Binds to the consensus sequence 5'-T[AG]TT[TG][AG][TC]-3' with variations of the sequence affecting onset of target gene expression. Activates a wide array of pharyngeal genes including ceh-22 and myo-2 and represses ectodermal genes lin-26 and elt-3, ensuring pharyngeal cell fate. Required for recruitment of htz-1 to a subset of pharyngeal promoters to ensure gene activation and also acts synergistically with tbx-2 in pharyngeal development. Acts in the regul [...] | 0.698 |
elt-6 | pop-1 | F52C12.5.2 | W10C8.2.1 | GATA-like transcription factor ELT-6. | Protein pop-1; Part of the Wnt signaling pathway essential for the specification of the mesodermal cell fate in early embryos. Required for asymmetrical division of somatic gonadal precursor descendants which initiate axis formation required to control organ shape. Represses expression of target genes via its interaction with hda-1 histone deacetylase. Required for specification of the M lineage-derived coelomocyte and sex myoblast fate. Regulates coelomocyte fate by positively regulating proliferation and ceh-34 and possibly eya-1 expression in M.dlpa and M.drpa precursors. | 0.448 |
end-3 | elt-1 | F58E10.5.1 | W09C2.1a.1 | GATA-type domain-containing protein. | Transcription factor elt-1; Transcriptional activator that binds to the consensus sequence 5'-[AT]GATA[AG]-3' and variations thereof. During embryonic development, required for specification of cell fate of major hypodermal (epidermal) cells at the blastomere stage. The requirement is true for all four lineages derived from ABarp, ABpra and C blastomeres. Required for seam cell maintenance in late embryogenesis, for proper formation of dauer larvae and locomotion. Regulates expression of bro-1, a regulator of seam cell proliferation, via a GATA-like binding motif. Probably represses ex [...] | 0.827 |
end-3 | elt-4 | F58E10.5.1 | C39B10.6a.1 | GATA-type domain-containing protein. | GATA-type domain-containing protein. | 0.891 |
end-3 | elt-6 | F58E10.5.1 | F52C12.5.2 | GATA-type domain-containing protein. | GATA-like transcription factor ELT-6. | 0.825 |
end-3 | med-1 | F58E10.5.1 | T24D3.1.1 | GATA-type domain-containing protein. | GATA-type domain-containing protein. | 0.945 |