STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
clpf-1Protein clpf-1; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation; Belongs to the Clp1 family. Clp1 subfamily. (428 aa)    
Predicted Functional Partners:
pcf-11
Polyadenylation and cleavage factor homolog 11.
   
 0.999
cri-3
Conserved regulator of innate immunity protein 3; Belongs to the MAM33 family.
 
 
  
 0.976
suf-1
Suf domain-containing protein.
   
 0.938
fipp-1
Fip1 domain-containing protein.
   
 0.934
tftc-3
Transcription Factor ThreeC subunit (GTF3C homolog).
   
 
 0.925
ZK1128.3
Uncharacterized protein ZK1128.3.
    
 
 0.918
bpnt-1
3'(2'), 5'-BisPhosphate NucleoTidase 1 homolog.
      
 0.911
cpsf-4
Cleavage and Polyadenylation Specificity Factor.
    
 0.901
cpsf-3
Cleavage and Polyadenylation Specificity Factor.
   
 0.896
cpsf-1
Probable cleavage and polyadenylation specificity factor subunit 1; CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity).
   
 0.838
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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