STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
clpf-1Protein clpf-1; Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation (428 aa)    
Predicted Functional Partners:
pcf-11
Polyadenylation and cleavage factor homolog 11; Protein PCF-11, isoform b (pcf-11) mRNA, complete cds
   
 0.997
cpsf-3
Cleavage and Polyadenylation Specificity Factor; Protein CPSF-3 (cpsf-3) mRNA, complete cds
   
 0.995
suf-1
SUppressor-of-Forked (Drosophila) homolog; Protein SUF-1 (suf-1) mRNA, complete cds
   
 0.994
cpf-2
Cleavage and Polyadenylation Factor; Protein CPF-2 (cpf-2) mRNA, complete cds
   
 0.994
cpsf-1
Probable cleavage and polyadenylation specificity factor subunit 1; CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity)
   
 0.993
cfim-2
Cleavage Factor IM (CFIm) homolog; Protein CFIM-2, isoform b
   
 0.991
cpsf-2
Probable cleavage and polyadenylation specificity factor subunit 2; CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition
   
 0.991
fipp-1
Factor Interacting with Poly(A) Polymerase; Protein FIPP-1 (fipp-1) mRNA, complete cds
   
 0.991
cpsf-4
Cleavage and Polyadenylation Specificity Factor; Protein CPSF-4 (cpsf-4) mRNA, complete cds
   
 0.988
symk-1
SYMpleKin cleavage and polyadenylation factor; Protein SYMK-1 (symk-1) mRNA, complete cds
   
 0.969
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Caenorhabditis elegans, Rhabditis elegans, roundworm
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