node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
acc-4 | acr-21 | T27E9.9.1 | F27B3.2a.1 | Acetylcholine-gated ion channel acc-4; Probable acetylcholine-gated chloride channel subunit. Does not have ion channel activity alone as a homopentamer, but forms a functional heteropentameric ion channel with acc-1. May function with lgc-46 to regulate synaptic transmission and synaptic vesicle release in response to acetylcholine in cholinergic motor neurons. | AcetylCholine Receptor. | 0.449 |
acc-4 | acr-23 | T27E9.9.1 | F59B1.9a.1 | Acetylcholine-gated ion channel acc-4; Probable acetylcholine-gated chloride channel subunit. Does not have ion channel activity alone as a homopentamer, but forms a functional heteropentameric ion channel with acc-1. May function with lgc-46 to regulate synaptic transmission and synaptic vesicle release in response to acetylcholine in cholinergic motor neurons. | Betaine receptor acr-23; Betaine receptor that functions as a ligand-gated non- selective monovalent cation channel in mechanosensory neurons to maintain basal levels of locomotion. The channel is permeable to Na(+) and K(+) but not to Ba(2+) or Ca(2+) ions. Elicits current in response to betaine, very weak current in response to choline, virtually no current in response to acetylcholine and nicotine, and no current in response to glycine and GABA. | 0.572 |
acr-21 | acc-4 | F27B3.2a.1 | T27E9.9.1 | AcetylCholine Receptor. | Acetylcholine-gated ion channel acc-4; Probable acetylcholine-gated chloride channel subunit. Does not have ion channel activity alone as a homopentamer, but forms a functional heteropentameric ion channel with acc-1. May function with lgc-46 to regulate synaptic transmission and synaptic vesicle release in response to acetylcholine in cholinergic motor neurons. | 0.449 |
acr-21 | acr-23 | F27B3.2a.1 | F59B1.9a.1 | AcetylCholine Receptor. | Betaine receptor acr-23; Betaine receptor that functions as a ligand-gated non- selective monovalent cation channel in mechanosensory neurons to maintain basal levels of locomotion. The channel is permeable to Na(+) and K(+) but not to Ba(2+) or Ca(2+) ions. Elicits current in response to betaine, very weak current in response to choline, virtually no current in response to acetylcholine and nicotine, and no current in response to glycine and GABA. | 0.596 |
acr-23 | acc-4 | F59B1.9a.1 | T27E9.9.1 | Betaine receptor acr-23; Betaine receptor that functions as a ligand-gated non- selective monovalent cation channel in mechanosensory neurons to maintain basal levels of locomotion. The channel is permeable to Na(+) and K(+) but not to Ba(2+) or Ca(2+) ions. Elicits current in response to betaine, very weak current in response to choline, virtually no current in response to acetylcholine and nicotine, and no current in response to glycine and GABA. | Acetylcholine-gated ion channel acc-4; Probable acetylcholine-gated chloride channel subunit. Does not have ion channel activity alone as a homopentamer, but forms a functional heteropentameric ion channel with acc-1. May function with lgc-46 to regulate synaptic transmission and synaptic vesicle release in response to acetylcholine in cholinergic motor neurons. | 0.572 |
acr-23 | acr-21 | F59B1.9a.1 | F27B3.2a.1 | Betaine receptor acr-23; Betaine receptor that functions as a ligand-gated non- selective monovalent cation channel in mechanosensory neurons to maintain basal levels of locomotion. The channel is permeable to Na(+) and K(+) but not to Ba(2+) or Ca(2+) ions. Elicits current in response to betaine, very weak current in response to choline, virtually no current in response to acetylcholine and nicotine, and no current in response to glycine and GABA. | AcetylCholine Receptor. | 0.596 |
acr-23 | ben-1 | F59B1.9a.1 | C54C6.2.1 | Betaine receptor acr-23; Betaine receptor that functions as a ligand-gated non- selective monovalent cation channel in mechanosensory neurons to maintain basal levels of locomotion. The channel is permeable to Na(+) and K(+) but not to Ba(2+) or Ca(2+) ions. Elicits current in response to betaine, very weak current in response to choline, virtually no current in response to acetylcholine and nicotine, and no current in response to glycine and GABA. | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | 0.691 |
acr-23 | ggr-2 | F59B1.9a.1 | C45B2.4a.1 | Betaine receptor acr-23; Betaine receptor that functions as a ligand-gated non- selective monovalent cation channel in mechanosensory neurons to maintain basal levels of locomotion. The channel is permeable to Na(+) and K(+) but not to Ba(2+) or Ca(2+) ions. Elicits current in response to betaine, very weak current in response to choline, virtually no current in response to acetylcholine and nicotine, and no current in response to glycine and GABA. | GABA/Glycine Receptor family (See gbr); Belongs to the ligand-gated ion channel (TC 1.A.9) family. | 0.772 |
acr-23 | lgc-40 | F59B1.9a.1 | T24D8.1.1 | Betaine receptor acr-23; Betaine receptor that functions as a ligand-gated non- selective monovalent cation channel in mechanosensory neurons to maintain basal levels of locomotion. The channel is permeable to Na(+) and K(+) but not to Ba(2+) or Ca(2+) ions. Elicits current in response to betaine, very weak current in response to choline, virtually no current in response to acetylcholine and nicotine, and no current in response to glycine and GABA. | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. | 0.582 |
acr-23 | lgc-48 | F59B1.9a.1 | C50B6.11.1 | Betaine receptor acr-23; Betaine receptor that functions as a ligand-gated non- selective monovalent cation channel in mechanosensory neurons to maintain basal levels of locomotion. The channel is permeable to Na(+) and K(+) but not to Ba(2+) or Ca(2+) ions. Elicits current in response to betaine, very weak current in response to choline, virtually no current in response to acetylcholine and nicotine, and no current in response to glycine and GABA. | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. | 0.736 |
acr-23 | lgc-52 | F59B1.9a.1 | Y73F8A.2.1 | Betaine receptor acr-23; Betaine receptor that functions as a ligand-gated non- selective monovalent cation channel in mechanosensory neurons to maintain basal levels of locomotion. The channel is permeable to Na(+) and K(+) but not to Ba(2+) or Ca(2+) ions. Elicits current in response to betaine, very weak current in response to choline, virtually no current in response to acetylcholine and nicotine, and no current in response to glycine and GABA. | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. | 0.562 |
acr-23 | lgc-54 | F59B1.9a.1 | T15B7.16.1 | Betaine receptor acr-23; Betaine receptor that functions as a ligand-gated non- selective monovalent cation channel in mechanosensory neurons to maintain basal levels of locomotion. The channel is permeable to Na(+) and K(+) but not to Ba(2+) or Ca(2+) ions. Elicits current in response to betaine, very weak current in response to choline, virtually no current in response to acetylcholine and nicotine, and no current in response to glycine and GABA. | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. | 0.608 |
acr-23 | snf-3 | F59B1.9a.1 | T13B5.1.1 | Betaine receptor acr-23; Betaine receptor that functions as a ligand-gated non- selective monovalent cation channel in mechanosensory neurons to maintain basal levels of locomotion. The channel is permeable to Na(+) and K(+) but not to Ba(2+) or Ca(2+) ions. Elicits current in response to betaine, very weak current in response to choline, virtually no current in response to acetylcholine and nicotine, and no current in response to glycine and GABA. | Sodium- and chloride-dependent betaine transporter; Betaine transporter dependent on Na(+) and Cl(-) ions that functions primarily in the epidermis to clear betaine from the extracellular space. Elicits current in response to betaine but not in response to GABA, L-carnitine, sarcosine, glycine or dimethylglycine. Belongs to the sodium:neurotransmitter symporter (SNF) family. | 0.704 |
acr-23 | unc-50 | F59B1.9a.1 | T07A5.2.1 | Betaine receptor acr-23; Betaine receptor that functions as a ligand-gated non- selective monovalent cation channel in mechanosensory neurons to maintain basal levels of locomotion. The channel is permeable to Na(+) and K(+) but not to Ba(2+) or Ca(2+) ions. Elicits current in response to betaine, very weak current in response to choline, virtually no current in response to acetylcholine and nicotine, and no current in response to glycine and GABA. | Protein unc-50; Required for cell surface expression of acetylcholine receptors in body-wall muscles. | 0.564 |
ben-1 | acr-23 | C54C6.2.1 | F59B1.9a.1 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | Betaine receptor acr-23; Betaine receptor that functions as a ligand-gated non- selective monovalent cation channel in mechanosensory neurons to maintain basal levels of locomotion. The channel is permeable to Na(+) and K(+) but not to Ba(2+) or Ca(2+) ions. Elicits current in response to betaine, very weak current in response to choline, virtually no current in response to acetylcholine and nicotine, and no current in response to glycine and GABA. | 0.691 |
ggr-2 | acr-23 | C45B2.4a.1 | F59B1.9a.1 | GABA/Glycine Receptor family (See gbr); Belongs to the ligand-gated ion channel (TC 1.A.9) family. | Betaine receptor acr-23; Betaine receptor that functions as a ligand-gated non- selective monovalent cation channel in mechanosensory neurons to maintain basal levels of locomotion. The channel is permeable to Na(+) and K(+) but not to Ba(2+) or Ca(2+) ions. Elicits current in response to betaine, very weak current in response to choline, virtually no current in response to acetylcholine and nicotine, and no current in response to glycine and GABA. | 0.772 |
lgc-40 | acr-23 | T24D8.1.1 | F59B1.9a.1 | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. | Betaine receptor acr-23; Betaine receptor that functions as a ligand-gated non- selective monovalent cation channel in mechanosensory neurons to maintain basal levels of locomotion. The channel is permeable to Na(+) and K(+) but not to Ba(2+) or Ca(2+) ions. Elicits current in response to betaine, very weak current in response to choline, virtually no current in response to acetylcholine and nicotine, and no current in response to glycine and GABA. | 0.582 |
lgc-48 | acr-23 | C50B6.11.1 | F59B1.9a.1 | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. | Betaine receptor acr-23; Betaine receptor that functions as a ligand-gated non- selective monovalent cation channel in mechanosensory neurons to maintain basal levels of locomotion. The channel is permeable to Na(+) and K(+) but not to Ba(2+) or Ca(2+) ions. Elicits current in response to betaine, very weak current in response to choline, virtually no current in response to acetylcholine and nicotine, and no current in response to glycine and GABA. | 0.736 |
lgc-52 | acr-23 | Y73F8A.2.1 | F59B1.9a.1 | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. | Betaine receptor acr-23; Betaine receptor that functions as a ligand-gated non- selective monovalent cation channel in mechanosensory neurons to maintain basal levels of locomotion. The channel is permeable to Na(+) and K(+) but not to Ba(2+) or Ca(2+) ions. Elicits current in response to betaine, very weak current in response to choline, virtually no current in response to acetylcholine and nicotine, and no current in response to glycine and GABA. | 0.562 |
lgc-54 | acr-23 | T15B7.16.1 | F59B1.9a.1 | Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. | Betaine receptor acr-23; Betaine receptor that functions as a ligand-gated non- selective monovalent cation channel in mechanosensory neurons to maintain basal levels of locomotion. The channel is permeable to Na(+) and K(+) but not to Ba(2+) or Ca(2+) ions. Elicits current in response to betaine, very weak current in response to choline, virtually no current in response to acetylcholine and nicotine, and no current in response to glycine and GABA. | 0.608 |