STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ver-4Tyrosine-protein kinase receptor ver-4; Receptor tyrosine kinase which may be involved, downstream of pvf-1, in the positioning of ray 1, the most anterior ray sensillum in the male tail. (1216 aa)    
Predicted Functional Partners:
sqst-5
Protein ver-2; May be involved, downstream of pvf-1, in the positioning of ray 1, the most anterior ray sensillum in the male tail.
      
 0.850
pvf-1
PDGF_2 domain-containing protein.
    
 0.816
gnrr-3
G_PROTEIN_RECEP_F1_2 domain-containing protein.
    
 
 0.762
baz-2
Bromodomain Adjacent to Zinc finger domain, 2A/2B, homolog.
    
 
 0.709
gnrr-2
G_PROTEIN_RECEP_F1_2 domain-containing protein.
    
 
 0.703
aap-1
Phosphoinositide 3-kinase adapter subunit.
    
 0.697
stg-2
STarGazin (Mammalian calcium channel) homolog.
    
 
 0.680
K09C6.8
Uncharacterized protein.
      
 0.661
plc-3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma plc-3; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) which plays an important role in the regulation of intracellular signaling cascades (Probable). Regulates basal and ovulatory sheath cell contractions by controlling Ca(2+) oscillations via IP3-mediated activation of IP3 receptor itr-1. In intestinal epithelial cells, regulates Ca(2+) oscillations which control posterior body wall muscle contractions required for defecation by IP3-mediated activation [...]
    
 0.649
gap-3
GTPase Activating Protein family.
    
 0.644
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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