STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H20J04.4Uncharacterized protein; Belongs to the DEAD box helicase family. (561 aa)    
Predicted Functional Partners:
rha-2
Putative ATP-dependent RNA helicase rha-2; Probable ATP-binding RNA helicase; Belongs to the DEAD box helicase family. DEAH subfamily.
  
 0.972
T01B7.5
Sas10 domain-containing protein.
   
 0.962
F57B10.8
Uncharacterized protein.
   
 
 0.948
ddx-52
DEAD boX helicase homolog.
  
0.930
wdr-46
WD_REPEATS_REGION domain-containing protein.
   
 0.929
Y41C4A.9
Uncharacterized protein.
   
 
 0.927
Y39A1A.14
Ribosomal RNA small subunit methyltransferase nep-1; S-adenosyl-L-methionine-dependent pseudouridine N(1)- methyltransferase that methylates a pseudouridine in 18S rRNA. Involved the biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3- carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA. Has also an essential role in 40S ribosomal subunit biogenesis independent on its methyltransferase activity, facilitating the incorporation of ribosomal protein S19 during the formation of pre- ribosomes; Belongs to the class IV-like SAM-binding methyltransferase superfami [...]
   
 0.922
krr-1
KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
   
 0.916
let-716
Uncharacterized protein.
  
 0.916
T26G10.1
Putative ATP-dependent RNA helicase T26G10.1; Probable ATP-dependent RNA helicase which may be involved in ribosome biogenesis.
  
 
0.910
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.