STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hxk-2Phosphotransferase. (552 aa)    
Predicted Functional Partners:
gpi-1
Glucose-6-phosphate isomerase; Belongs to the GPI family.
 
 
 
 0.927
pgk-1
Probable phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
   
  
 0.880
pyk-2
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 
 0.844
pyk-1
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 
 0.819
gsy-1
Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan; Belongs to the glycosyltransferase 3 family.
   
  
 0.807
pfk-1.1
ATP-dependent 6-phosphofructokinase 1; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
   
  
 0.805
icl-1
Bifunctional glyoxylate cycle protein; In the C-terminal section; belongs to the malate synthase family.
   
  
 0.771
ZK632.4
Probable mannose-6-phosphate isomerase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.
  
 
 0.715
R05F9.6
Uncharacterized protein; Belongs to the phosphohexose mutase family.
   
 
 0.700
enol-1
Enolase; Belongs to the enolase family.
   
  
 0.694
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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