STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
clik-3CaLponIn-liKe proteins. (202 aa)    
Predicted Functional Partners:
F42H10.3
LIM and SH3 domain protein F42H10.3.
   
  
 0.742
aex-2
G-protein coupled receptor aex-2; G-protein coupled receptor for the nlp-40 neuropeptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Plays a role in the defecation motor program, which is a coordinated series of three muscle contractions that occurs every 45 seconds. Specifically, acts in GABAergic neurons, such as AVL and DVB, to control the expulsion step of defecation. Required for fatty acid uptake and metabolism by intestinal cells and therefore regulates the levels of triglycerides in the intestine.
      
 0.660
cpn-4
Calponin-homology (CH) domain-containing protein.
   
  
 0.511
cpn-3
Calponin-homology (CH) domain-containing protein.
   
  
 0.497
C44C10.3
MFS domain-containing protein.
   
  
 0.475
ZK370.4
Uncharacterized NTE family protein ZK370.4; Belongs to the NTE family.
      
 0.465
C31H5.1
Uncharacterized protein.
      
 0.463
M110.7
Uncharacterized NTE family protein M110.7.
      
 0.463
ZC376.3
COesterase domain-containing protein.
      
 0.461
tmd-2
TropoMoDulin.
      
 0.459
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.