STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cyp-35B1CYtochrome P450 family; Belongs to the cytochrome P450 family. (499 aa)    
Predicted Functional Partners:
pks-1
PolyKetide Synthase.
  
 0.811
flr-4
Serine/threonine-protein kinase flr-4; Probable serine-threonine protein kinase involved in the control of defecation rhythms. Required to increase the length of defecation cycle period. Acts in a cell-functional rather than developmental aspect in the regulation of defecation rhythms.
   
 
 0.794
stdh-2
Putative steroid dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.
  
 0.756
T20F5.4
Uncharacterized protein.
      
 0.740
stdh-3
Putative steroid dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.
  
 0.728
ugt-25
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
 
 0.707
cyp-32B1
CYtochrome P450 family; Belongs to the cytochrome P450 family.
  
 
 0.694
ugt-41
UDP-GlucuronosylTransferase.
   
 
 0.643
drl-1
Protein drl-1; Negatively regulates lifespan and health span probably by participating in nutrient sensing.
   
 
 0.601
dhs-26
DeHydrogenases, Short chain; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.590
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.