STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sdz-24OB domain-containing protein. (236 aa)    
Predicted Functional Partners:
F10D2.8
Uncharacterized protein.
   
  
 0.852
K01A2.10
Uncharacterized protein.
      
 0.808
Y95B8A.6
Uncharacterized protein.
      
 0.806
dna-2
Yeast DNA helicase/endonuclease family.
    
 
 0.764
xpf-1
ERCC4 domain-containing protein.
    
 
 0.736
atl-1
Serine/threonine-protein kinase ATR; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor (By similarity). Recognizes the substrate consensus sequence [ST]-Q (By similarity). Phosphorylates various proteins, which collectively inhibits DNA replication and mitosis and promotes DNA repair and recombination (By similarity). Prevents mitotic catastrophe by functioning in the S-phase checkpoint and cooperating with atm-1 in the c [...]
    
 
 0.736
sld-5
DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family.
   
 
 0.725
F42A6.5
BRCT domain-containing protein.
   
 
 0.713
rpa-4
RPA_C domain-containing protein.
   
 
 0.712
rpa-2
RPA_C domain-containing protein.
   
 
 0.712
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (18%) [HD]