node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
gly-7 | gly-9 | Y46H3A.6a.1 | Y47D3A.23a.1 | Probable N-acetylgalactosaminyltransferase 7; Probable glycopeptide transferase involved in O-linked oligosaccharide biosynthesis. Glycopeptide transferases catalyze the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide (By similarity). In contrast to other members of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on peptides that have been tested. Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified; Belongs to t [...] | Probable N-acetylgalactosaminyltransferase 9; Probable glycopeptide transferase involved in O-linked oligosaccharide biosynthesis. Glycopeptide transferases catalyze the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide (By similarity). In contrast to other members of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on peptides that have been tested. Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified. | 0.615 |
gly-7 | tyr-2 | Y46H3A.6a.1 | K08E3.1.1 | Probable N-acetylgalactosaminyltransferase 7; Probable glycopeptide transferase involved in O-linked oligosaccharide biosynthesis. Glycopeptide transferases catalyze the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide (By similarity). In contrast to other members of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on peptides that have been tested. Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified; Belongs to t [...] | TYRosinase. | 0.805 |
gly-9 | gly-7 | Y47D3A.23a.1 | Y46H3A.6a.1 | Probable N-acetylgalactosaminyltransferase 9; Probable glycopeptide transferase involved in O-linked oligosaccharide biosynthesis. Glycopeptide transferases catalyze the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide (By similarity). In contrast to other members of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on peptides that have been tested. Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified. | Probable N-acetylgalactosaminyltransferase 7; Probable glycopeptide transferase involved in O-linked oligosaccharide biosynthesis. Glycopeptide transferases catalyze the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide (By similarity). In contrast to other members of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on peptides that have been tested. Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified; Belongs to t [...] | 0.615 |
gly-9 | tyr-2 | Y47D3A.23a.1 | K08E3.1.1 | Probable N-acetylgalactosaminyltransferase 9; Probable glycopeptide transferase involved in O-linked oligosaccharide biosynthesis. Glycopeptide transferases catalyze the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide (By similarity). In contrast to other members of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on peptides that have been tested. Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified. | TYRosinase. | 0.698 |
grl-21 | tyr-2 | ZC168.5.1 | K08E3.1.1 | Ground-like domain-containing protein. | TYRosinase. | 0.436 |
hif-1 | nhr-57 | F38A6.3b.1 | T05B4.2.1 | Hypoxia-inducible factor 1; A transcription factor which is a key regulator in various cellular processes; including environment stress resistance (oxygen levels, hydrogen sulfide and cyanide levels and heat), negative regulation of cell apoptosis in ASJ neurons by inhibition of cep-1 via transcriptional activation of tyr-2, resistance/susceptibility to pathogenic bacteria, lifespan and brood size. Involved in mediating susceptibility to enteropathogenic E.coli. Increased levels of hif-1 activity confer resistance to P.aeruginosa-mediated death but also confer susceptibility to S.aureu [...] | Nuclear hormone receptor family member nhr-57; Orphan nuclear receptor; Belongs to the nuclear hormone receptor family. | 0.794 |
hif-1 | tyr-2 | F38A6.3b.1 | K08E3.1.1 | Hypoxia-inducible factor 1; A transcription factor which is a key regulator in various cellular processes; including environment stress resistance (oxygen levels, hydrogen sulfide and cyanide levels and heat), negative regulation of cell apoptosis in ASJ neurons by inhibition of cep-1 via transcriptional activation of tyr-2, resistance/susceptibility to pathogenic bacteria, lifespan and brood size. Involved in mediating susceptibility to enteropathogenic E.coli. Increased levels of hif-1 activity confer resistance to P.aeruginosa-mediated death but also confer susceptibility to S.aureu [...] | TYRosinase. | 0.660 |
hif-1 | vhl-1 | F38A6.3b.1 | F08G12.4.1 | Hypoxia-inducible factor 1; A transcription factor which is a key regulator in various cellular processes; including environment stress resistance (oxygen levels, hydrogen sulfide and cyanide levels and heat), negative regulation of cell apoptosis in ASJ neurons by inhibition of cep-1 via transcriptional activation of tyr-2, resistance/susceptibility to pathogenic bacteria, lifespan and brood size. Involved in mediating susceptibility to enteropathogenic E.coli. Increased levels of hif-1 activity confer resistance to P.aeruginosa-mediated death but also confer susceptibility to S.aureu [...] | Von Hippel-Lindau tumor suppressor homolog; Involved in the response to variation in environmental oxygen levels by targeting the hypoxia-inducible transcription factor hif-1 for proteasomal degradation when oxygen levels are normal (around 20%). By regulating hif-1 expression, plays a role in iron homeostasis, aging, heat acclimation and progeny size. Mediates resistance to enteropathogenic E.coli. Mediates susceptibility to B.thuringiensis pore-forming toxins. Not involved in P.aeruginosa susceptibility. Belongs to the VHL family. | 0.998 |
nhr-57 | hif-1 | T05B4.2.1 | F38A6.3b.1 | Nuclear hormone receptor family member nhr-57; Orphan nuclear receptor; Belongs to the nuclear hormone receptor family. | Hypoxia-inducible factor 1; A transcription factor which is a key regulator in various cellular processes; including environment stress resistance (oxygen levels, hydrogen sulfide and cyanide levels and heat), negative regulation of cell apoptosis in ASJ neurons by inhibition of cep-1 via transcriptional activation of tyr-2, resistance/susceptibility to pathogenic bacteria, lifespan and brood size. Involved in mediating susceptibility to enteropathogenic E.coli. Increased levels of hif-1 activity confer resistance to P.aeruginosa-mediated death but also confer susceptibility to S.aureu [...] | 0.794 |
nhr-57 | oac-54 | T05B4.2.1 | W07A12.6.1 | Nuclear hormone receptor family member nhr-57; Orphan nuclear receptor; Belongs to the nuclear hormone receptor family. | Acyl_transf_3 domain-containing protein. | 0.440 |
nhr-57 | tyr-2 | T05B4.2.1 | K08E3.1.1 | Nuclear hormone receptor family member nhr-57; Orphan nuclear receptor; Belongs to the nuclear hormone receptor family. | TYRosinase. | 0.587 |
nhr-57 | vhl-1 | T05B4.2.1 | F08G12.4.1 | Nuclear hormone receptor family member nhr-57; Orphan nuclear receptor; Belongs to the nuclear hormone receptor family. | Von Hippel-Lindau tumor suppressor homolog; Involved in the response to variation in environmental oxygen levels by targeting the hypoxia-inducible transcription factor hif-1 for proteasomal degradation when oxygen levels are normal (around 20%). By regulating hif-1 expression, plays a role in iron homeostasis, aging, heat acclimation and progeny size. Mediates resistance to enteropathogenic E.coli. Mediates susceptibility to B.thuringiensis pore-forming toxins. Not involved in P.aeruginosa susceptibility. Belongs to the VHL family. | 0.820 |
oac-54 | nhr-57 | W07A12.6.1 | T05B4.2.1 | Acyl_transf_3 domain-containing protein. | Nuclear hormone receptor family member nhr-57; Orphan nuclear receptor; Belongs to the nuclear hormone receptor family. | 0.440 |
oac-54 | tyr-1 | W07A12.6.1 | C02C2.1.1 | Acyl_transf_3 domain-containing protein. | Putative tyrosinase-like protein tyr-1; Belongs to the tyrosinase family. | 0.697 |
oac-54 | tyr-2 | W07A12.6.1 | K08E3.1.1 | Acyl_transf_3 domain-containing protein. | TYRosinase. | 0.740 |
trp-2 | tyr-2 | R06B10.4b.1 | K08E3.1.1 | TRP (Transient receptor potential) channel family; Belongs to the transient receptor (TC 1.A.4) family. | TYRosinase. | 0.468 |
tyr-1 | oac-54 | C02C2.1.1 | W07A12.6.1 | Putative tyrosinase-like protein tyr-1; Belongs to the tyrosinase family. | Acyl_transf_3 domain-containing protein. | 0.697 |
tyr-1 | tyr-2 | C02C2.1.1 | K08E3.1.1 | Putative tyrosinase-like protein tyr-1; Belongs to the tyrosinase family. | TYRosinase. | 0.657 |
tyr-1 | unc-89 | C02C2.1.1 | C09D1.1b.1 | Putative tyrosinase-like protein tyr-1; Belongs to the tyrosinase family. | Muscle M-line assembly protein unc-89; Structural component of the muscle M line which is involved in assembly and organization of sarcomere myofilaments. The large isoform a, isoform b, isoform d and isoform f play an essential role in maintaining the organization of sarcomeres but not myofilament alignment during body wall muscle development whereas the small isoform c and isoform d appear to have a minor role. Isoform b and isoform f are required for the organization of unc-15/paramyosin into sarcomere thick filaments in body wall muscles. By binding mel-26, a substrate adapter of t [...] | 0.501 |
tyr-2 | gly-7 | K08E3.1.1 | Y46H3A.6a.1 | TYRosinase. | Probable N-acetylgalactosaminyltransferase 7; Probable glycopeptide transferase involved in O-linked oligosaccharide biosynthesis. Glycopeptide transferases catalyze the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide (By similarity). In contrast to other members of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on peptides that have been tested. Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified; Belongs to t [...] | 0.805 |