node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
actl-1 | ilc-17.1 | C15B12.6a.1 | T22H6.1.1 | ACT1-like protein; May act as an adapter to facilitate downstream signaling for the receptor complex composed of ilcr-1 and ilcr-2, which is a signaling complex that modulates neuronal activity and animal behavior in response to sensory neuron input. | Interleukin cytokine-related protein 17.1; Ligand for the receptor complex composed of ilcr-1 and ilcr- 2. Binding to the ilcr-1/2 receptor complex triggers a signaling cascade, activating the downsteam signaling components actl-1, pik-1 and nfki-1, and results in increased neuronal activity in RMG interneurons in response to input from oxygen-sensing neurons. This leads to increased animal movement and promotes aggregation behavior. Plays a role in the responsiveness of RMG interneurons to ascaroside pheromones; Belongs to the IL-17 family. | 0.911 |
actl-1 | ilcr-1 | C15B12.6a.1 | Y64G10A.6.1 | ACT1-like protein; May act as an adapter to facilitate downstream signaling for the receptor complex composed of ilcr-1 and ilcr-2, which is a signaling complex that modulates neuronal activity and animal behavior in response to sensory neuron input. | Interleukin cytokine receptor-related protein 1; Forms a receptor complex together with receptor ilcr-2, which upon activation acts as a modulator of neuronal activity. Binding of the ligand ilc-17.1 to the ilcr-1/2 receptor complex triggers a signaling cascade that activates the downsteam signaling components actl-1, pik-1 and nfki-1, and results in increased neuronal activity in RMG interneurons in response to input from oxygen-sensing neurons. This leads to increased animal movement and promotes aggregation behavior. | 0.942 |
actl-1 | ilcr-2 | C15B12.6a.1 | F56D1.2.1 | ACT1-like protein; May act as an adapter to facilitate downstream signaling for the receptor complex composed of ilcr-1 and ilcr-2, which is a signaling complex that modulates neuronal activity and animal behavior in response to sensory neuron input. | Interleukin cytokine receptor-related protein 2; Forms a receptor complex together with receptor ilcr-1, which upon activation acts as a modulator of neuronal activity. Binding of the ligand ilc-17.1 to the ilcr-1/2 receptor complex triggers a signaling cascade that activates the downsteam signaling components actl-1, pik-1 and nfki-1, and results in increased neuronal activity in RMG interneurons in response to input from oxygen-sensing neurons. This leads to increased animal movement and promotes aggregation behavior. | 0.936 |
actl-1 | pik-1 | C15B12.6a.1 | K09B11.1a.2 | ACT1-like protein; May act as an adapter to facilitate downstream signaling for the receptor complex composed of ilcr-1 and ilcr-2, which is a signaling complex that modulates neuronal activity and animal behavior in response to sensory neuron input. | Pelle-like serine/threonine-protein kinase pik-1; Through association with the adapter actl-1, may act downstream of the receptor complex composed of ilcr-1 and ilcr-2, which is a signaling complex that modulates neuronal activity and animal behavior in response to sensory neuron input. | 0.900 |
ikb-1 | peli-1 | C04F12.3.1 | F25B4.2.1 | ANK_REP_REGION domain-containing protein. | PELI1 and PELI2 related. | 0.400 |
ikb-1 | pik-1 | C04F12.3.1 | K09B11.1a.2 | ANK_REP_REGION domain-containing protein. | Pelle-like serine/threonine-protein kinase pik-1; Through association with the adapter actl-1, may act downstream of the receptor complex composed of ilcr-1 and ilcr-2, which is a signaling complex that modulates neuronal activity and animal behavior in response to sensory neuron input. | 0.923 |
ikb-1 | tol-1 | C04F12.3.1 | C07F11.1.1 | ANK_REP_REGION domain-containing protein. | TIR domain-containing protein. | 0.909 |
ikb-1 | trf-1 | C04F12.3.1 | F45G2.6.1 | ANK_REP_REGION domain-containing protein. | TNF Receptor Associated Factor (TRAF) homolog. | 0.912 |
ilc-17.1 | actl-1 | T22H6.1.1 | C15B12.6a.1 | Interleukin cytokine-related protein 17.1; Ligand for the receptor complex composed of ilcr-1 and ilcr- 2. Binding to the ilcr-1/2 receptor complex triggers a signaling cascade, activating the downsteam signaling components actl-1, pik-1 and nfki-1, and results in increased neuronal activity in RMG interneurons in response to input from oxygen-sensing neurons. This leads to increased animal movement and promotes aggregation behavior. Plays a role in the responsiveness of RMG interneurons to ascaroside pheromones; Belongs to the IL-17 family. | ACT1-like protein; May act as an adapter to facilitate downstream signaling for the receptor complex composed of ilcr-1 and ilcr-2, which is a signaling complex that modulates neuronal activity and animal behavior in response to sensory neuron input. | 0.911 |
ilc-17.1 | ilcr-1 | T22H6.1.1 | Y64G10A.6.1 | Interleukin cytokine-related protein 17.1; Ligand for the receptor complex composed of ilcr-1 and ilcr- 2. Binding to the ilcr-1/2 receptor complex triggers a signaling cascade, activating the downsteam signaling components actl-1, pik-1 and nfki-1, and results in increased neuronal activity in RMG interneurons in response to input from oxygen-sensing neurons. This leads to increased animal movement and promotes aggregation behavior. Plays a role in the responsiveness of RMG interneurons to ascaroside pheromones; Belongs to the IL-17 family. | Interleukin cytokine receptor-related protein 1; Forms a receptor complex together with receptor ilcr-2, which upon activation acts as a modulator of neuronal activity. Binding of the ligand ilc-17.1 to the ilcr-1/2 receptor complex triggers a signaling cascade that activates the downsteam signaling components actl-1, pik-1 and nfki-1, and results in increased neuronal activity in RMG interneurons in response to input from oxygen-sensing neurons. This leads to increased animal movement and promotes aggregation behavior. | 0.907 |
ilc-17.1 | ilcr-2 | T22H6.1.1 | F56D1.2.1 | Interleukin cytokine-related protein 17.1; Ligand for the receptor complex composed of ilcr-1 and ilcr- 2. Binding to the ilcr-1/2 receptor complex triggers a signaling cascade, activating the downsteam signaling components actl-1, pik-1 and nfki-1, and results in increased neuronal activity in RMG interneurons in response to input from oxygen-sensing neurons. This leads to increased animal movement and promotes aggregation behavior. Plays a role in the responsiveness of RMG interneurons to ascaroside pheromones; Belongs to the IL-17 family. | Interleukin cytokine receptor-related protein 2; Forms a receptor complex together with receptor ilcr-1, which upon activation acts as a modulator of neuronal activity. Binding of the ligand ilc-17.1 to the ilcr-1/2 receptor complex triggers a signaling cascade that activates the downsteam signaling components actl-1, pik-1 and nfki-1, and results in increased neuronal activity in RMG interneurons in response to input from oxygen-sensing neurons. This leads to increased animal movement and promotes aggregation behavior. | 0.947 |
ilc-17.1 | pik-1 | T22H6.1.1 | K09B11.1a.2 | Interleukin cytokine-related protein 17.1; Ligand for the receptor complex composed of ilcr-1 and ilcr- 2. Binding to the ilcr-1/2 receptor complex triggers a signaling cascade, activating the downsteam signaling components actl-1, pik-1 and nfki-1, and results in increased neuronal activity in RMG interneurons in response to input from oxygen-sensing neurons. This leads to increased animal movement and promotes aggregation behavior. Plays a role in the responsiveness of RMG interneurons to ascaroside pheromones; Belongs to the IL-17 family. | Pelle-like serine/threonine-protein kinase pik-1; Through association with the adapter actl-1, may act downstream of the receptor complex composed of ilcr-1 and ilcr-2, which is a signaling complex that modulates neuronal activity and animal behavior in response to sensory neuron input. | 0.764 |
ilcr-1 | actl-1 | Y64G10A.6.1 | C15B12.6a.1 | Interleukin cytokine receptor-related protein 1; Forms a receptor complex together with receptor ilcr-2, which upon activation acts as a modulator of neuronal activity. Binding of the ligand ilc-17.1 to the ilcr-1/2 receptor complex triggers a signaling cascade that activates the downsteam signaling components actl-1, pik-1 and nfki-1, and results in increased neuronal activity in RMG interneurons in response to input from oxygen-sensing neurons. This leads to increased animal movement and promotes aggregation behavior. | ACT1-like protein; May act as an adapter to facilitate downstream signaling for the receptor complex composed of ilcr-1 and ilcr-2, which is a signaling complex that modulates neuronal activity and animal behavior in response to sensory neuron input. | 0.942 |
ilcr-1 | ilc-17.1 | Y64G10A.6.1 | T22H6.1.1 | Interleukin cytokine receptor-related protein 1; Forms a receptor complex together with receptor ilcr-2, which upon activation acts as a modulator of neuronal activity. Binding of the ligand ilc-17.1 to the ilcr-1/2 receptor complex triggers a signaling cascade that activates the downsteam signaling components actl-1, pik-1 and nfki-1, and results in increased neuronal activity in RMG interneurons in response to input from oxygen-sensing neurons. This leads to increased animal movement and promotes aggregation behavior. | Interleukin cytokine-related protein 17.1; Ligand for the receptor complex composed of ilcr-1 and ilcr- 2. Binding to the ilcr-1/2 receptor complex triggers a signaling cascade, activating the downsteam signaling components actl-1, pik-1 and nfki-1, and results in increased neuronal activity in RMG interneurons in response to input from oxygen-sensing neurons. This leads to increased animal movement and promotes aggregation behavior. Plays a role in the responsiveness of RMG interneurons to ascaroside pheromones; Belongs to the IL-17 family. | 0.907 |
ilcr-1 | ilcr-2 | Y64G10A.6.1 | F56D1.2.1 | Interleukin cytokine receptor-related protein 1; Forms a receptor complex together with receptor ilcr-2, which upon activation acts as a modulator of neuronal activity. Binding of the ligand ilc-17.1 to the ilcr-1/2 receptor complex triggers a signaling cascade that activates the downsteam signaling components actl-1, pik-1 and nfki-1, and results in increased neuronal activity in RMG interneurons in response to input from oxygen-sensing neurons. This leads to increased animal movement and promotes aggregation behavior. | Interleukin cytokine receptor-related protein 2; Forms a receptor complex together with receptor ilcr-1, which upon activation acts as a modulator of neuronal activity. Binding of the ligand ilc-17.1 to the ilcr-1/2 receptor complex triggers a signaling cascade that activates the downsteam signaling components actl-1, pik-1 and nfki-1, and results in increased neuronal activity in RMG interneurons in response to input from oxygen-sensing neurons. This leads to increased animal movement and promotes aggregation behavior. | 0.959 |
ilcr-1 | pik-1 | Y64G10A.6.1 | K09B11.1a.2 | Interleukin cytokine receptor-related protein 1; Forms a receptor complex together with receptor ilcr-2, which upon activation acts as a modulator of neuronal activity. Binding of the ligand ilc-17.1 to the ilcr-1/2 receptor complex triggers a signaling cascade that activates the downsteam signaling components actl-1, pik-1 and nfki-1, and results in increased neuronal activity in RMG interneurons in response to input from oxygen-sensing neurons. This leads to increased animal movement and promotes aggregation behavior. | Pelle-like serine/threonine-protein kinase pik-1; Through association with the adapter actl-1, may act downstream of the receptor complex composed of ilcr-1 and ilcr-2, which is a signaling complex that modulates neuronal activity and animal behavior in response to sensory neuron input. | 0.787 |
ilcr-2 | actl-1 | F56D1.2.1 | C15B12.6a.1 | Interleukin cytokine receptor-related protein 2; Forms a receptor complex together with receptor ilcr-1, which upon activation acts as a modulator of neuronal activity. Binding of the ligand ilc-17.1 to the ilcr-1/2 receptor complex triggers a signaling cascade that activates the downsteam signaling components actl-1, pik-1 and nfki-1, and results in increased neuronal activity in RMG interneurons in response to input from oxygen-sensing neurons. This leads to increased animal movement and promotes aggregation behavior. | ACT1-like protein; May act as an adapter to facilitate downstream signaling for the receptor complex composed of ilcr-1 and ilcr-2, which is a signaling complex that modulates neuronal activity and animal behavior in response to sensory neuron input. | 0.936 |
ilcr-2 | ilc-17.1 | F56D1.2.1 | T22H6.1.1 | Interleukin cytokine receptor-related protein 2; Forms a receptor complex together with receptor ilcr-1, which upon activation acts as a modulator of neuronal activity. Binding of the ligand ilc-17.1 to the ilcr-1/2 receptor complex triggers a signaling cascade that activates the downsteam signaling components actl-1, pik-1 and nfki-1, and results in increased neuronal activity in RMG interneurons in response to input from oxygen-sensing neurons. This leads to increased animal movement and promotes aggregation behavior. | Interleukin cytokine-related protein 17.1; Ligand for the receptor complex composed of ilcr-1 and ilcr- 2. Binding to the ilcr-1/2 receptor complex triggers a signaling cascade, activating the downsteam signaling components actl-1, pik-1 and nfki-1, and results in increased neuronal activity in RMG interneurons in response to input from oxygen-sensing neurons. This leads to increased animal movement and promotes aggregation behavior. Plays a role in the responsiveness of RMG interneurons to ascaroside pheromones; Belongs to the IL-17 family. | 0.947 |
ilcr-2 | ilcr-1 | F56D1.2.1 | Y64G10A.6.1 | Interleukin cytokine receptor-related protein 2; Forms a receptor complex together with receptor ilcr-1, which upon activation acts as a modulator of neuronal activity. Binding of the ligand ilc-17.1 to the ilcr-1/2 receptor complex triggers a signaling cascade that activates the downsteam signaling components actl-1, pik-1 and nfki-1, and results in increased neuronal activity in RMG interneurons in response to input from oxygen-sensing neurons. This leads to increased animal movement and promotes aggregation behavior. | Interleukin cytokine receptor-related protein 1; Forms a receptor complex together with receptor ilcr-2, which upon activation acts as a modulator of neuronal activity. Binding of the ligand ilc-17.1 to the ilcr-1/2 receptor complex triggers a signaling cascade that activates the downsteam signaling components actl-1, pik-1 and nfki-1, and results in increased neuronal activity in RMG interneurons in response to input from oxygen-sensing neurons. This leads to increased animal movement and promotes aggregation behavior. | 0.959 |
ilcr-2 | pik-1 | F56D1.2.1 | K09B11.1a.2 | Interleukin cytokine receptor-related protein 2; Forms a receptor complex together with receptor ilcr-1, which upon activation acts as a modulator of neuronal activity. Binding of the ligand ilc-17.1 to the ilcr-1/2 receptor complex triggers a signaling cascade that activates the downsteam signaling components actl-1, pik-1 and nfki-1, and results in increased neuronal activity in RMG interneurons in response to input from oxygen-sensing neurons. This leads to increased animal movement and promotes aggregation behavior. | Pelle-like serine/threonine-protein kinase pik-1; Through association with the adapter actl-1, may act downstream of the receptor complex composed of ilcr-1 and ilcr-2, which is a signaling complex that modulates neuronal activity and animal behavior in response to sensory neuron input. | 0.778 |