STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dhs-8DeHydrogenases, Short chain. (379 aa)    
Predicted Functional Partners:
sdz-8
SKN-1 Dependent Zygotic transcript.
   
 
 0.921
dhs-6
SCP2 domain-containing protein.
  
 0.850
gsto-2
Probable glutathione transferase omega-2; Exhibits glutathione-dependent thiol transferase activity. Has dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) (By similarity); Belongs to the GST superfamily. Omega family.
   
  
 0.839
pks-1
PolyKetide Synthase.
  
 0.839
brap-2
BRCA1-associated protein homolog 2; Controls the stress response to increased levels of reactive oxygen species by modulating the brc-1-dependent expression of cki-1.
      
 0.805
ugt-13
UDP-GlucuronosylTransferase.
   
 
 0.780
C55A6.6
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.752
F20G2.1
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 
 0.745
C07D8.6
Aldo_ket_red domain-containing protein.
  
 
 0.729
gst-7
Probable glutathione S-transferase 7; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles (By similarity). May play a role in the detoxification of reactive oxygen species produced during pathogenic bacterial infection. Belongs to the GST superfamily. Sigma family.
   
  
 0.706
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.