node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C29E4.10 | W02F12.2 | C29E4.10.1 | W02F12.2.1 | Putative galactocerebrosidase; Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Belongs to the glycosyl hydrolase 59 family. | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid; Belongs to the alkaline ceramidase family. | 0.916 |
C29E4.10 | asah-1 | C29E4.10.1 | K11D2.2.1 | Putative galactocerebrosidase; Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Belongs to the glycosyl hydrolase 59 family. | Acid ceramidase subunit alpha; Lysosomal ceramidase that hydrolyzes sphingolipid ceramides into sphingosine and free fatty acids at acidic pH. | 0.974 |
C29E4.10 | asm-2 | C29E4.10.1 | ZK455.4.1 | Putative galactocerebrosidase; Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Belongs to the glycosyl hydrolase 59 family. | Sphingomyelin phosphodiesterase 2; Converts sphingomyelin to ceramide. Belongs to the acid sphingomyelinase family. | 0.916 |
C29E4.10 | asm-3 | C29E4.10.1 | W03G1.7a.1 | Putative galactocerebrosidase; Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Belongs to the glycosyl hydrolase 59 family. | Putative sphingomyelin phosphodiesterase asm-3; Converts sphingomyelin to ceramide. Belongs to the acid sphingomyelinase family. | 0.916 |
C29E4.10 | cerk-1 | C29E4.10.1 | T10B11.2.1 | Putative galactocerebrosidase; Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Belongs to the glycosyl hydrolase 59 family. | Ceramide kinase 1; Catalyzes the phosphorylation of ceramide to form ceramide 1- phosphate. | 0.936 |
C29E4.10 | gba-1 | C29E4.10.1 | C33C12.3a.1 | Putative galactocerebrosidase; Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Belongs to the glycosyl hydrolase 59 family. | Putative glucosylceramidase 1. | 0.971 |
C29E4.10 | gba-2 | C29E4.10.1 | C33C12.8.1 | Putative galactocerebrosidase; Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Belongs to the glycosyl hydrolase 59 family. | Putative glucosylceramidase 2; Belongs to the glycosyl hydrolase 30 family. | 0.977 |
C29E4.10 | gba-4 | C29E4.10.1 | Y4C6B.6.1 | Putative galactocerebrosidase; Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Belongs to the glycosyl hydrolase 59 family. | Putative glucosylceramidase 4; Belongs to the glycosyl hydrolase 30 family. | 0.971 |
C29E4.10 | sms-1 | C29E4.10.1 | H21P03.3b.1 | Putative galactocerebrosidase; Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Belongs to the glycosyl hydrolase 59 family. | Phosphatidylcholine:ceramide cholinephosphotransferase 1; Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. | 0.933 |
W02F12.2 | C29E4.10 | W02F12.2.1 | C29E4.10.1 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid; Belongs to the alkaline ceramidase family. | Putative galactocerebrosidase; Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Belongs to the glycosyl hydrolase 59 family. | 0.916 |
W02F12.2 | asah-1 | W02F12.2.1 | K11D2.2.1 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid; Belongs to the alkaline ceramidase family. | Acid ceramidase subunit alpha; Lysosomal ceramidase that hydrolyzes sphingolipid ceramides into sphingosine and free fatty acids at acidic pH. | 0.977 |
W02F12.2 | asm-2 | W02F12.2.1 | ZK455.4.1 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid; Belongs to the alkaline ceramidase family. | Sphingomyelin phosphodiesterase 2; Converts sphingomyelin to ceramide. Belongs to the acid sphingomyelinase family. | 0.909 |
W02F12.2 | asm-3 | W02F12.2.1 | W03G1.7a.1 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid; Belongs to the alkaline ceramidase family. | Putative sphingomyelin phosphodiesterase asm-3; Converts sphingomyelin to ceramide. Belongs to the acid sphingomyelinase family. | 0.929 |
W02F12.2 | cerk-1 | W02F12.2.1 | T10B11.2.1 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid; Belongs to the alkaline ceramidase family. | Ceramide kinase 1; Catalyzes the phosphorylation of ceramide to form ceramide 1- phosphate. | 0.989 |
W02F12.2 | gba-1 | W02F12.2.1 | C33C12.3a.1 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid; Belongs to the alkaline ceramidase family. | Putative glucosylceramidase 1. | 0.903 |
W02F12.2 | gba-2 | W02F12.2.1 | C33C12.8.1 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid; Belongs to the alkaline ceramidase family. | Putative glucosylceramidase 2; Belongs to the glycosyl hydrolase 30 family. | 0.903 |
W02F12.2 | gba-4 | W02F12.2.1 | Y4C6B.6.1 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid; Belongs to the alkaline ceramidase family. | Putative glucosylceramidase 4; Belongs to the glycosyl hydrolase 30 family. | 0.903 |
W02F12.2 | sms-1 | W02F12.2.1 | H21P03.3b.1 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid; Belongs to the alkaline ceramidase family. | Phosphatidylcholine:ceramide cholinephosphotransferase 1; Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. | 0.978 |
W02F12.2 | sphk-1 | W02F12.2.1 | C34C6.5a.1 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid; Belongs to the alkaline ceramidase family. | Sphingosine kinase 1; Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on sphinganine (By similarity). Required for neurotransmitter release from neuromuscular junctions. Acts by recruiting the synaptic vesicle priming protein unc-13 to synapses (Probable). | 0.959 |
asah-1 | C29E4.10 | K11D2.2.1 | C29E4.10.1 | Acid ceramidase subunit alpha; Lysosomal ceramidase that hydrolyzes sphingolipid ceramides into sphingosine and free fatty acids at acidic pH. | Putative galactocerebrosidase; Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Belongs to the glycosyl hydrolase 59 family. | 0.974 |