STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
K11H12.9Protein kinase domain-containing protein. (378 aa)    
Predicted Functional Partners:
nhr-76
Nuclear Hormone Receptor family; Belongs to the nuclear hormone receptor family.
 
    
 0.809
mrpl-2
Ribosomal_L2_C domain-containing protein.
   
 
 0.671
mrps-5
Putative 28S ribosomal protein S5, mitochondrial; Belongs to the universal ribosomal protein uS5 family.
   
 
 0.659
gmeb-1
SAND domain-containing protein.
   
  
 0.639
mrps-12
Mitochondrial Ribosomal Protein, Small; Belongs to the universal ribosomal protein uS12 family.
   
 
 0.594
mrpl-38
Mitochondrial Ribosomal Protein, Large.
   
   0.592
jkk-1
Dual specificity mitogen-activated protein kinase kinase jkk-1; Dual specificity protein kinase which acts as an essential component of the JNK signal transduction pathway. May phosphorylate jnk-1. Plays a role in coordinating locomotion via D-type GABAergic motoneurons and in regulating synaptic vesicle transport downstream of adapter protein unc-16 and probably by activating jnk-1. Positively regulates lifespan. Upon environmental stress such as heat stress regulates daf-16 nuclear translocation probably by activating jnk-1. Regulates germline cell apoptosis in response to heavy meta [...]
   
 
 0.590
Y92H12BR.3
Uncharacterized protein Y92H12BR.3.
   
   0.572
mrpl-41
39S ribosomal protein L41, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL41 family.
   
 
 0.571
mrps-2
Mitochondrial Ribosomal Protein, Small.
   
 
 0.564
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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