node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ctf-8 | ncs-6 | T22C1.4.1 | W09G10.3.1 | Chromosome Transmission Fidelity factor homolog. | Neuronal Calcium Sensor family. | 0.805 |
ctf-8 | snf-6 | T22C1.4.1 | M01G5.5.1 | Chromosome Transmission Fidelity factor homolog. | Sodium-dependent acetylcholine transporter; Mediates sodium-dependent uptake of acetylcholine at neuromuscular junctions during periods of increased synaptic activity, may also prevent spillover to adjacent synaptic sites. Not involved in the uptake of other neurotransmitters (GABA, glycine, proline and glutamate) and there was also no inhibition of uptake by adding an excess of other candidate substrates (GABA, glycine, taurine, creatine, proline, alanine, carnitine, glutamate and betaine). Required for muscle integrity; altered transport of acetylcholine due to loss of dystrophin-gly [...] | 0.691 |
dyb-1 | dyc-1 | F47G6.1a.1 | C33G3.1b.1 | Dystrobrevin-1; Plays a role in cholinergic transmission and as a functional partner of dystrophin (dys-1), necessary for muscle maintenance. | Dystrophin-like protein 1; Together with dys-1 and hlh-1, participates in a common muscular function. | 0.909 |
dyb-1 | dys-1 | F47G6.1a.1 | F15D3.1a.1 | Dystrobrevin-1; Plays a role in cholinergic transmission and as a functional partner of dystrophin (dys-1), necessary for muscle maintenance. | Dystrophin-1; Plays a role in cholinergic transmission and as a functional partner of dystrobrevin (dyb-1), necessary for muscle maintenance. Required for neuronal positioning. | 0.976 |
dyb-1 | islo-1 | F47G6.1a.1 | F42G8.5.1 | Dystrobrevin-1; Plays a role in cholinergic transmission and as a functional partner of dystrophin (dys-1), necessary for muscle maintenance. | Interactor with SLO-1. | 0.695 |
dyb-1 | sgn-1 | F47G6.1a.1 | F07H5.2.1 | Dystrobrevin-1; Plays a role in cholinergic transmission and as a functional partner of dystrophin (dys-1), necessary for muscle maintenance. | SarcoGlycaN. | 0.934 |
dyb-1 | slo-1 | F47G6.1a.1 | Y51A2D.19d.1 | Dystrobrevin-1; Plays a role in cholinergic transmission and as a functional partner of dystrophin (dys-1), necessary for muscle maintenance. | Calcium-activated potassium channel slo-1; Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Essential for the regulation of neurotransmitter release at synapses. | 0.813 |
dyb-1 | snf-6 | F47G6.1a.1 | M01G5.5.1 | Dystrobrevin-1; Plays a role in cholinergic transmission and as a functional partner of dystrophin (dys-1), necessary for muscle maintenance. | Sodium-dependent acetylcholine transporter; Mediates sodium-dependent uptake of acetylcholine at neuromuscular junctions during periods of increased synaptic activity, may also prevent spillover to adjacent synaptic sites. Not involved in the uptake of other neurotransmitters (GABA, glycine, proline and glutamate) and there was also no inhibition of uptake by adding an excess of other candidate substrates (GABA, glycine, taurine, creatine, proline, alanine, carnitine, glutamate and betaine). Required for muscle integrity; altered transport of acetylcholine due to loss of dystrophin-gly [...] | 0.700 |
dyb-1 | stn-1 | F47G6.1a.1 | F30A10.8.1 | Dystrobrevin-1; Plays a role in cholinergic transmission and as a functional partner of dystrophin (dys-1), necessary for muscle maintenance. | Syntrophin-1; Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex (DGC). May also act by slowing calcium channel activity via a direct or indirect mechanism potentially involving other second messengers. Plays an early role in the formation of the neuromuscular junction and is necessary for muscle maintenance. | 0.996 |
dyb-1 | stn-2 | F47G6.1a.1 | F27D9.8b.1 | Dystrobrevin-1; Plays a role in cholinergic transmission and as a functional partner of dystrophin (dys-1), necessary for muscle maintenance. | PDZ domain-containing protein. | 0.946 |
dyc-1 | dyb-1 | C33G3.1b.1 | F47G6.1a.1 | Dystrophin-like protein 1; Together with dys-1 and hlh-1, participates in a common muscular function. | Dystrobrevin-1; Plays a role in cholinergic transmission and as a functional partner of dystrophin (dys-1), necessary for muscle maintenance. | 0.909 |
dyc-1 | dys-1 | C33G3.1b.1 | F15D3.1a.1 | Dystrophin-like protein 1; Together with dys-1 and hlh-1, participates in a common muscular function. | Dystrophin-1; Plays a role in cholinergic transmission and as a functional partner of dystrobrevin (dyb-1), necessary for muscle maintenance. Required for neuronal positioning. | 0.958 |
dyc-1 | sgn-1 | C33G3.1b.1 | F07H5.2.1 | Dystrophin-like protein 1; Together with dys-1 and hlh-1, participates in a common muscular function. | SarcoGlycaN. | 0.866 |
dyc-1 | slo-1 | C33G3.1b.1 | Y51A2D.19d.1 | Dystrophin-like protein 1; Together with dys-1 and hlh-1, participates in a common muscular function. | Calcium-activated potassium channel slo-1; Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Essential for the regulation of neurotransmitter release at synapses. | 0.496 |
dyc-1 | snf-6 | C33G3.1b.1 | M01G5.5.1 | Dystrophin-like protein 1; Together with dys-1 and hlh-1, participates in a common muscular function. | Sodium-dependent acetylcholine transporter; Mediates sodium-dependent uptake of acetylcholine at neuromuscular junctions during periods of increased synaptic activity, may also prevent spillover to adjacent synaptic sites. Not involved in the uptake of other neurotransmitters (GABA, glycine, proline and glutamate) and there was also no inhibition of uptake by adding an excess of other candidate substrates (GABA, glycine, taurine, creatine, proline, alanine, carnitine, glutamate and betaine). Required for muscle integrity; altered transport of acetylcholine due to loss of dystrophin-gly [...] | 0.561 |
dyc-1 | stn-1 | C33G3.1b.1 | F30A10.8.1 | Dystrophin-like protein 1; Together with dys-1 and hlh-1, participates in a common muscular function. | Syntrophin-1; Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex (DGC). May also act by slowing calcium channel activity via a direct or indirect mechanism potentially involving other second messengers. Plays an early role in the formation of the neuromuscular junction and is necessary for muscle maintenance. | 0.906 |
dyc-1 | stn-2 | C33G3.1b.1 | F27D9.8b.1 | Dystrophin-like protein 1; Together with dys-1 and hlh-1, participates in a common muscular function. | PDZ domain-containing protein. | 0.788 |
dys-1 | dyb-1 | F15D3.1a.1 | F47G6.1a.1 | Dystrophin-1; Plays a role in cholinergic transmission and as a functional partner of dystrobrevin (dyb-1), necessary for muscle maintenance. Required for neuronal positioning. | Dystrobrevin-1; Plays a role in cholinergic transmission and as a functional partner of dystrophin (dys-1), necessary for muscle maintenance. | 0.976 |
dys-1 | dyc-1 | F15D3.1a.1 | C33G3.1b.1 | Dystrophin-1; Plays a role in cholinergic transmission and as a functional partner of dystrobrevin (dyb-1), necessary for muscle maintenance. Required for neuronal positioning. | Dystrophin-like protein 1; Together with dys-1 and hlh-1, participates in a common muscular function. | 0.958 |
dys-1 | islo-1 | F15D3.1a.1 | F42G8.5.1 | Dystrophin-1; Plays a role in cholinergic transmission and as a functional partner of dystrobrevin (dyb-1), necessary for muscle maintenance. Required for neuronal positioning. | Interactor with SLO-1. | 0.811 |