STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dao-2DB domain-containing protein. (136 aa)    
Predicted Functional Partners:
wrt-10
WaRThog (Hedgehog-like family).
   
  
 0.718
dao-4
Dauer or Aging adult Overexpression.
   
  
 0.668
Y55F3BL.4
SRR1 domain-containing protein.
   
   0.647
dao-5
Nucleolar protein dao-5; Nucleolar protein which binds to RNA polymerase I and rDNA and is required for efficient RNA polymerase I-mediated rDNA transcription. Maintains the epigenetically active status of rDNA chromatin which facilitates rDNA transcription and sustains germline development, ensuring fertility. Plays a role in the modulation of nucleolus size. May play a role in the regulation of lifespan. Belongs to the NOLC1 family.
   
  
 0.628
noah-1
NOmpA Homolog (Drosophila nompA: no mechanoreceptor potential A).
   
   0.618
dpy-3
Col_cuticle_N domain-containing protein.
   
   0.618
dpy-7
Cuticle collagen dpy-7; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. Mutations in dpy-7 affects the body shape.
   
   0.618
dao-6
Dauer or Aging adult Overexpression.
      
 0.613
mrpl-23
Probable 39S ribosomal protein L23, mitochondrial; Belongs to the universal ribosomal protein uL23 family.
   
 
 0.610
lpr-3
LiPocalin-Related protein.
   
    0.587
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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