Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| E02D9.1 | M117.3 | E02D9.1a.1 | M117.3.1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | 14_3_3 domain-containing protein. | 0.752 |
| E02D9.1 | ksr-1 | E02D9.1a.1 | F13B9.5.2 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | Kinase suppressor of Ras A; Serine/threonine-protein kinase which positively regulates Ras-mediated signaling probably acting at the level of let-60/ras or/and lin-45/raf. Involved in sex myoblast migration. Plays a role in responses to M.nematophilum-mediated bacterial infection by promoting tail swelling and preventing constipation. Functions redundantly with ksr-2 in the Ras-mediated regulation of larval survival, the development of excretory canal and in mpk-1 phosphorylation in somatic cells. In addition, involved in determining vulval precursor cell fate during vulval induction i [...] | 0.902 |
| E02D9.1 | ksr-2 | E02D9.1a.1 | F58D5.4a.1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | Kinase suppressor of Ras B; Probable inactive protein kinase which positively regulates Ras-mediated signaling probably acting at the level of let-60/ras or/and lin-45/raf. In the germline, regulates meiotic progression during oogenesis and mpk-1 (isoform b) phosphorylation. Plays a role in meiotic recombination events. Functions redundantly with ksr-1 in the Ras-mediated regulation of larval survival, the development of excretory canal, in determining vulval precursor cell fate during vulval induction and in mpk-1 phosphorylation in somatic cells. | 0.913 |
| E02D9.1 | lin-45 | E02D9.1a.1 | Y73B6A.5b.1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | Raf homolog serine/threonine-protein kinase; Protein kinase that participates in the induction of vulva and has roles in fertility and viability. Acts downstream of the Ras protein let-60. Required for progression of developing oocytes through the pachytene stage. Plays a role in responses to M.nematophilum- mediated bacterial infection by promoting tail swelling and preventing constipation. Positively regulates lifespan upstream of mek-2 and mpk-1. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. | 0.944 |
| E02D9.1 | mek-2 | E02D9.1a.1 | Y54E10BL.6.1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | Dual specificity mitogen-activated protein kinase kinase mek-2; Functions in the let-60 Ras signaling pathway; acts downstream of lin-45 raf kinase, but before the sur-1/mpk-1 gene product in controlling vulval cell differentiation. Required for progression of developing oocytes through the pachytene stage. Plays a role in responses to M.nematophilum- mediated bacterial infection by promoting tail swelling and preventing constipation. Involved in fluid homeostasis. Positively regulates lifespan upstream of mpk-1. | 0.827 |
| M117.3 | E02D9.1 | M117.3.1 | E02D9.1a.1 | 14_3_3 domain-containing protein. | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | 0.752 |
| M117.3 | cdc-25.1 | M117.3.1 | K06A5.7.2 | 14_3_3 domain-containing protein. | M-phase inducer phosphatase cdc-25.1. | 0.735 |
| M117.3 | cdc-25.2 | M117.3.1 | F16B4.8a.1 | 14_3_3 domain-containing protein. | M-phase inducer phosphatase cdc-25.2; Required for intestinal cell division following the 16E cell stage of embryogenesis. Regulates intestinal cell divisions and binucleations probably by modulating the activity of the cell cycle regulator wee-1.3 and by activating the cdk-1/cyb-1 complex. Belongs to the MPI phosphatase family. | 0.735 |
| M117.3 | cdc-25.3 | M117.3.1 | ZK637.11.1 | 14_3_3 domain-containing protein. | M-phase inducer phosphatase cdc-25.3. | 0.735 |
| M117.3 | cdc-25.4 | M117.3.1 | R05H5.2.1 | 14_3_3 domain-containing protein. | Rhodanese domain-containing protein. | 0.735 |
| M117.3 | ksr-1 | M117.3.1 | F13B9.5.2 | 14_3_3 domain-containing protein. | Kinase suppressor of Ras A; Serine/threonine-protein kinase which positively regulates Ras-mediated signaling probably acting at the level of let-60/ras or/and lin-45/raf. Involved in sex myoblast migration. Plays a role in responses to M.nematophilum-mediated bacterial infection by promoting tail swelling and preventing constipation. Functions redundantly with ksr-2 in the Ras-mediated regulation of larval survival, the development of excretory canal and in mpk-1 phosphorylation in somatic cells. In addition, involved in determining vulval precursor cell fate during vulval induction i [...] | 0.750 |
| M117.3 | ksr-2 | M117.3.1 | F58D5.4a.1 | 14_3_3 domain-containing protein. | Kinase suppressor of Ras B; Probable inactive protein kinase which positively regulates Ras-mediated signaling probably acting at the level of let-60/ras or/and lin-45/raf. In the germline, regulates meiotic progression during oogenesis and mpk-1 (isoform b) phosphorylation. Plays a role in meiotic recombination events. Functions redundantly with ksr-1 in the Ras-mediated regulation of larval survival, the development of excretory canal, in determining vulval precursor cell fate during vulval induction and in mpk-1 phosphorylation in somatic cells. | 0.750 |
| M117.3 | lin-45 | M117.3.1 | Y73B6A.5b.1 | 14_3_3 domain-containing protein. | Raf homolog serine/threonine-protein kinase; Protein kinase that participates in the induction of vulva and has roles in fertility and viability. Acts downstream of the Ras protein let-60. Required for progression of developing oocytes through the pachytene stage. Plays a role in responses to M.nematophilum- mediated bacterial infection by promoting tail swelling and preventing constipation. Positively regulates lifespan upstream of mek-2 and mpk-1. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. | 0.896 |
| M117.3 | mek-2 | M117.3.1 | Y54E10BL.6.1 | 14_3_3 domain-containing protein. | Dual specificity mitogen-activated protein kinase kinase mek-2; Functions in the let-60 Ras signaling pathway; acts downstream of lin-45 raf kinase, but before the sur-1/mpk-1 gene product in controlling vulval cell differentiation. Required for progression of developing oocytes through the pachytene stage. Plays a role in responses to M.nematophilum- mediated bacterial infection by promoting tail swelling and preventing constipation. Involved in fluid homeostasis. Positively regulates lifespan upstream of mpk-1. | 0.752 |
| M117.3 | yap-1 | M117.3.1 | F13E6.4.1 | 14_3_3 domain-containing protein. | Yes-associated protein homolog 1; Plays a role in thermal stress response and in aging. | 0.755 |
| cdc-25.1 | M117.3 | K06A5.7.2 | M117.3.1 | M-phase inducer phosphatase cdc-25.1. | 14_3_3 domain-containing protein. | 0.735 |
| cdc-25.1 | cdc-25.2 | K06A5.7.2 | F16B4.8a.1 | M-phase inducer phosphatase cdc-25.1. | M-phase inducer phosphatase cdc-25.2; Required for intestinal cell division following the 16E cell stage of embryogenesis. Regulates intestinal cell divisions and binucleations probably by modulating the activity of the cell cycle regulator wee-1.3 and by activating the cdk-1/cyb-1 complex. Belongs to the MPI phosphatase family. | 0.639 |
| cdc-25.1 | cdc-25.3 | K06A5.7.2 | ZK637.11.1 | M-phase inducer phosphatase cdc-25.1. | M-phase inducer phosphatase cdc-25.3. | 0.617 |
| cdc-25.1 | cdc-25.4 | K06A5.7.2 | R05H5.2.1 | M-phase inducer phosphatase cdc-25.1. | Rhodanese domain-containing protein. | 0.538 |
| cdc-25.2 | M117.3 | F16B4.8a.1 | M117.3.1 | M-phase inducer phosphatase cdc-25.2; Required for intestinal cell division following the 16E cell stage of embryogenesis. Regulates intestinal cell divisions and binucleations probably by modulating the activity of the cell cycle regulator wee-1.3 and by activating the cdk-1/cyb-1 complex. Belongs to the MPI phosphatase family. | 14_3_3 domain-containing protein. | 0.735 |
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