node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F25B5.6 | F52B11.2 | F25B5.6b.1 | F52B11.2a.1 | Putative folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Probable phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions; Belongs to the eukaryotic PMM family. | 0.423 |
F25B5.6 | R10H10.6 | F25B5.6b.1 | R10H10.6.1 | Putative folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Flavokinase domain-containing protein. | 0.733 |
F25B5.6 | alh-13 | F25B5.6b.1 | T22H6.2b.1 | Putative folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Probable delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.772 |
F25B5.6 | cat-4 | F25B5.6b.1 | F32G8.6.1 | Putative folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | GTP cyclohydrolase 1; Involved in serotonin and dopamine biosynthesis that affects movement, mating behavior, foraging behavior, and cell migration. | 0.867 |
F25B5.6 | cor-1 | F25B5.6b.1 | R01H10.3c.2 | Putative folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Coronin-like protein cor-1; Required to direct the migration of Q neuroblasts along the anterior axis of the body during larval development. This is dependent on its asymmetric expression in Q neuroblasts. Belongs to the WD repeat coronin family. | 0.856 |
F25B5.6 | dhfr-1 | F25B5.6b.1 | C36B1.7.1 | Putative folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Putative dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity). | 0.998 |
F25B5.6 | dut-1 | F25B5.6b.1 | K07A1.2.3 | Putative folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Deoxyuridinetriphosphatase. | 0.627 |
F52B11.2 | F25B5.6 | F52B11.2a.1 | F25B5.6b.1 | Probable phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions; Belongs to the eukaryotic PMM family. | Putative folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.423 |
F52B11.2 | R10H10.6 | F52B11.2a.1 | R10H10.6.1 | Probable phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions; Belongs to the eukaryotic PMM family. | Flavokinase domain-containing protein. | 0.649 |
F52B11.2 | alh-13 | F52B11.2a.1 | T22H6.2b.1 | Probable phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions; Belongs to the eukaryotic PMM family. | Probable delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.719 |
F52B11.2 | cat-4 | F52B11.2a.1 | F32G8.6.1 | Probable phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions; Belongs to the eukaryotic PMM family. | GTP cyclohydrolase 1; Involved in serotonin and dopamine biosynthesis that affects movement, mating behavior, foraging behavior, and cell migration. | 0.418 |
F52B11.2 | cor-1 | F52B11.2a.1 | R01H10.3c.2 | Probable phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions; Belongs to the eukaryotic PMM family. | Coronin-like protein cor-1; Required to direct the migration of Q neuroblasts along the anterior axis of the body during larval development. This is dependent on its asymmetric expression in Q neuroblasts. Belongs to the WD repeat coronin family. | 0.872 |
F52B11.2 | dhfr-1 | F52B11.2a.1 | C36B1.7.1 | Probable phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions; Belongs to the eukaryotic PMM family. | Putative dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity). | 0.510 |
R10H10.6 | F25B5.6 | R10H10.6.1 | F25B5.6b.1 | Flavokinase domain-containing protein. | Putative folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.733 |
R10H10.6 | F52B11.2 | R10H10.6.1 | F52B11.2a.1 | Flavokinase domain-containing protein. | Probable phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions; Belongs to the eukaryotic PMM family. | 0.649 |
R10H10.6 | alh-13 | R10H10.6.1 | T22H6.2b.1 | Flavokinase domain-containing protein. | Probable delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.798 |
R10H10.6 | cat-4 | R10H10.6.1 | F32G8.6.1 | Flavokinase domain-containing protein. | GTP cyclohydrolase 1; Involved in serotonin and dopamine biosynthesis that affects movement, mating behavior, foraging behavior, and cell migration. | 0.738 |
R10H10.6 | cor-1 | R10H10.6.1 | R01H10.3c.2 | Flavokinase domain-containing protein. | Coronin-like protein cor-1; Required to direct the migration of Q neuroblasts along the anterior axis of the body during larval development. This is dependent on its asymmetric expression in Q neuroblasts. Belongs to the WD repeat coronin family. | 0.741 |
R10H10.6 | dhfr-1 | R10H10.6.1 | C36B1.7.1 | Flavokinase domain-containing protein. | Putative dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity). | 0.590 |
act-5 | cor-1 | T25C8.2.2 | R01H10.3c.2 | ACTin. | Coronin-like protein cor-1; Required to direct the migration of Q neuroblasts along the anterior axis of the body during larval development. This is dependent on its asymmetric expression in Q neuroblasts. Belongs to the WD repeat coronin family. | 0.721 |