STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aass-1AminoAdipate-Semialdehyde Synthase homolog. (952 aa)    
Predicted Functional Partners:
alh-9
Putative aldehyde dehydrogenase family 7 member A1 homolog; Belongs to the aldehyde dehydrogenase family.
  
 
 0.961
spds-1
PABS domain-containing protein; Belongs to the spermidine/spermine synthase family.
 
  
 0.942
slc-25A18.1
SLC (SoLute Carrier) homolog; Belongs to the mitochondrial carrier (TC 2.A.29) family.
   
  
 0.915
slc-25A29
SLC (SoLute Carrier) homolog; Belongs to the mitochondrial carrier (TC 2.A.29) family.
   
  
 0.895
gdh-1
Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
  
 0.856
W09D6.1
AMP-binding domain-containing protein.
  
 
 0.853
pks-1
PolyKetide Synthase.
  
 
 0.824
immt-1
MICOS complex subunit MIC60-1; Sustains mitochondrial morphology probably through maintaining cristae morphology. May act as a component of the MICOS complex, a large protein complex of the mitochondria (By similarity).
   
  
 0.815
gly-8
Probable N-acetylgalactosaminyltransferase 8; Potential glycopeptide transferase involved in O-linked oligosaccharide biosynthesis (By similarity). In contrast to other members of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on peptides that have been tested. Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified.
   
  
 0.814
F53F10.2
Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
  
 
 0.803
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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